Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3707047 | 0.81 | SMYD3 (0.45) | KDM4EKMT2ASMYD3OPRM1 | |
| SCHEMBL2330731 | 0.79 | OPRM1 (0.35) | KDM4EKMT2AOPRM1 | |
| SCHEMBL23579242 | 0.77 | OPRM1 (0.34) | KDM4EKMT2AOPRM1 | |
| SCHEMBL22495635 | 0.76 | SMYD3 (0.42) | KDM4EKMT2ASMYD3OPRM1 | |
| SCHEMBL2324649 | 0.75 | CYP2D6 (0.36) | KDM4EKMT2AOPRM1 | |
| SCHEMBL3713521 | 0.74 | SMYD3 (0.37) | KDM4EKMT2ASMYD3OPRM1 | |
| SCHEMBL21233081 | 0.74 | KDM4E (0.32) | KDM4EKMT2ASMYD3 | |
| SCHEMBL28485735 | 0.74 | KDM4E (0.33) | KDM4EKMT2ASMYD3OPRM1 | |
| SCHEMBL25477687 | 0.72 | ADH1B (0.37) | — | |
| SCHEMBL22434968 | 0.70 | KDM4E (0.46) | KDM4EKMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356108-B1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI SA (FR) | 2014-10-15 | — | — | EP | disclosed |
| EP-2356108-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010055267-A1 | CARBAMATE DERIVATIVES OF ALKYL-HETEROCYCLES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2010-05-20 | — | — | WO | disclosed |