SCHEMBL23328482

SCHEMBL23328482

N#Cc1ccc(-c2ccc(N(c3ccc(-c4ccc(C#N)c(C#N)c4)cc3)c3ccc(-c4ccc5sc6ccccc6c5c4)cc3)cc2)cc1C#N

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.37
ALDH1A1 P00352 3/20 0.36
KDM4E B2RXH2 1/20 0.36
HTT P42858 1/20 0.36
RXFP1 Q9HBX9 1/20 0.36
LMNA P02545 1/20 0.36
THRB P10828 1/20 0.36
MAOB P27338 3/20 0.34
MAOA P21397 2/20 0.34
MAPT P10636 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PIM3 Q86V86 1/20 0.32
CYP11B1 P15538 1/20 0.32
CYP11B2 P19099 1/20 0.32
PTGIR P43119 1/20 0.32
CYP1A2 P05177 1/20 0.32
MCL1 Q07820 1/20 0.31
ESR1 P03372 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25544533 1.00 GPR3 (0.37) GPR3ALDH1A1KDM4EHTTRXFP1
SCHEMBL25543481 0.96 GPR3 (0.36) GPR3ALDH1A1KDM4EHTTRXFP1
SCHEMBL25544698 0.96 GPR3 (0.36) GPR3ALDH1A1KDM4EHTTRXFP1
SCHEMBL25544699 0.92 PRSS12 (0.37) GPR3ALDH1A1KDM4EHTTRXFP1
SCHEMBL23328508 0.89 SLC22A12 (0.38) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL21691498 0.88 GPR3 (0.42) GPR3ALDH1A1KDM4EHTTRXFP1
SCHEMBL23328483 0.86 PRSS12 (0.41) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL23328465 0.86 PRSS12 (0.41) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL25544160 0.86 PRSS12 (0.41) GPR3ALDH1A1MAPTHPGDRAB9A
SCHEMBL25548015 0.86 PRSS12 (0.41) GPR3ALDH1A1MAPTHPGDRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021085817-A2 TERTIARY AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING SAME 주식회사 랩토 2021-05-06 WO disclosed