Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.45 |
| ▸ | CHAT | P28329 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RAD52 | P43351 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2335846 | 1.00 | RAB9A (0.45) | RAB9ARCE1CHATMAPTMAPK1 | |
| SCHEMBL18334832 | 0.87 | LOXL2 (0.44) | RAB9ARCE1SMN1; SMN2NPSR1KDM4E | |
| SCHEMBL18823593 | 0.81 | RAB9A (0.51) | RAB9ARCE1CHATMAPTMAPK1 | |
| SCHEMBL5804296 | 0.79 | RAB9A (0.46) | RAB9ARCE1CHATMAPTMAPK1 | |
| SCHEMBL18334833 | 0.77 | LOXL2 (0.33) | — | |
| Iodide SCHEMBL25373170 | 0.76 | LOXL2 (0.32) | — | |
| Iodide SCHEMBL25374247 | 0.76 | LOXL2 (0.32) | — | |
| SCHEMBL2335412 | 0.71 | RAB9A (0.42) | RAB9ARCE1CHATMAPTMAPK1 | |
| SCHEMBL30611103 | 0.71 | RAB9A (0.69) | RAB9ARCE1CHATMAPTMAPK1 | |
| SCHEMBL16053326 | 0.70 | RAB9A (0.41) | RAB9ARCE1CHATMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2533815-A1 | NUCLEIC ACID COMPLEXES | Procarta Biosystems Ltd (GB) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011098829-A1 | NUCLEIC ACID COMPLEXES | PROCARTA BIOSYSTEMS LTD (GB) | 2011-08-18 | — | — | WO | disclosed |