Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.40 |
| ▸ | TET3 | O43151 | 8/20 | 0.40 |
| ▸ | FBXL19 | Q6PCT2 | 8/20 | 0.40 |
| ▸ | KDM2B | Q8NHM5 | 8/20 | 0.40 |
| ▸ | CXXC4 | Q9H2H0 | 8/20 | 0.40 |
| ▸ | KDM2A | Q9Y2K7 | 8/20 | 0.40 |
| ▸ | CXXC5 | Q7LFL8 | 7/20 | 0.40 |
| ▸ | TET1 | Q8NFU7 | 6/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | BTK | Q06187 | 4/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | TEC | P42680 | 1/20 | 0.31 |
| ▸ | TXK | P42681 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
| ▸ | JAK3 | P52333 | 3/20 | 0.31 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21707127 | 0.94 | BTK (0.37) | KMT2ATET3FBXL19KDM2BCXXC4 | |
| SCHEMBL23328553 | 0.92 | KMT2A (0.41) | KMT2ATET3FBXL19KDM2BCXXC4 | |
| SCHEMBL16075250 | 0.90 | JAK3 (0.35) | KMT2ATET3FBXL19KDM2BCXXC4 | |
| SCHEMBL23179807 | 0.85 | BTK (0.35) | KMT2ATET3FBXL19KDM2BCXXC4 | |
| SCHEMBL21287863 | 0.80 | ALDH1A1 (0.45) | KMT2AHSD11B1USP2 | |
| SCHEMBL16075261 | 0.80 | JAK3 (0.36) | KMT2ATET3FBXL19KDM2BCXXC4 | |
| SCHEMBL17773331 | 0.79 | HRH3 (0.38) | KMT2ATET3FBXL19KDM2BCXXC4 | |
| SCHEMBL20849781 | 0.79 | TET3 (0.45) | KMT2ATET3FBXL19KDM2BCXXC4 | |
| SCHEMBL19889017 | 0.78 | HSD11B1 (0.46) | KMT2ATET3FBXL19KDM2BCXXC4 | |
| SCHEMBL18806125 | 0.75 | HSD11B1 (0.38) | KMT2AHSD11B1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11365196-B2 | FGFR inhibitor and application thereof | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2022-06-21 | — | — | US | disclosed |
| US-20210130353-A1 | FGFR INHIBITOR AND APPLICATION THEREOF | BETTA PHARMACEUTICALS CO., LTD. (CN) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11365196-B2 | FGFR inhibitor and application thereof | FGFR1, FGFR4, FGFR2 | KMT2A 3253/4885TET3 4452/4885FBXL19 1700/4885 |
| US-20210130353-A1 | FGFR INHIBITOR AND APPLICATION THEREOF | FGFR1, FGFR4, FGFR2 | KMT2A 3272/4885TET3 4625/4885FBXL19 1869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.