SCHEMBL23328735

SCHEMBL23328735

CCCCNC(=O)NCCCS(=O)(=O)O

nearest known ligand 0.68

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 8/20 0.68
EPHX1 P07099 8/20 0.67
MEN1 O00255 1/20 0.46
HTT P42858 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 2/20 0.45
ALDH1A1 P00352 1/20 0.45
LMNA P02545 1/20 0.45
ALB P02768 1/20 0.45
CYP2C9 P11712 1/20 0.45
TSHR P16473 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL917710 0.94 EPHX2 (0.76) EPHX2EPHX1
SCHEMBL918144 0.94 EPHX2 (0.76) EPHX2EPHX1
SCHEMBL13330471 0.92 EPHX1 (0.64) EPHX2EPHX1MEN1KMT2A
SCHEMBL23328387 0.92 EPHX1 (0.67) EPHX2EPHX1MEN1HTTKMT2A
SCHEMBL14178998 0.89 EPHX2 (0.58) EPHX2EPHX1MEN1KMT2AALDH1A1
SCHEMBL30786047 0.85 EPHX1 (0.90) EPHX2EPHX1
SCHEMBL23329077 0.84 EPHX2 (0.50) EPHX2EPHX1MEN1HTTKMT2A
SCHEMBL23328732 0.84 EPHX1 (0.67) EPHX2EPHX1MEN1HTTKMT2A
SCHEMBL17991831 0.84 EPHX2 (0.55) EPHX2EPHX1MEN1HTTKMT2A
SCHEMBL17133784 0.83 EPHX1 (0.95) EPHX2EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11701333-B2 Antibacterial compounds Kent Innovation & Enterprise (GB) 2023-07-18 US disclosed
US-11701333-B2 Antibacterial compounds Kent Innovation & Enterprise (GB) 2023-07-18 US disclosed
US-20210128501-A1 ANTIBACTERIAL COMPOUNDS KENT INNOVATION & ENTERPRISE, UNIVERSITY OF KENT (GB) 2021-05-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11701333-B2 Antibacterial compounds ARF1, ARL1, TLR1 EPHX2 2581/4885EPHX1 2158/4885MEN1 1300/4885
US-20210128501-A1 ANTIBACTERIAL COMPOUNDS ARF1, ARL1, TLR1 EPHX2 2581/4885EPHX1 2158/4885MEN1 1300/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.