SCHEMBL2332946

SCHEMBL2332946

c1ccc(Nc2ccc3[nH]c4ccc(Nc5ccccc5)cc4c3c2)cc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.54
HSD17B10 Q99714 3/20 0.54
TSHR P16473 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
ALOX12 P18054 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
ALOX15 P16050 1/20 0.54
PTGS1 P23219 1/20 0.54
SLC6A2 P23975 1/20 0.54
MAPK1 P28482 1/20 0.54
PTGS2 P35354 1/20 0.54
HTR2B P41595 1/20 0.54
KMT2A Q03164 3/20 0.54
MAPT P10636 3/20 0.54
MEN1 O00255 2/20 0.54
AR P10275 1/20 0.54
CYP3A4 P08684 3/20 0.50
HPGD P15428 2/20 0.50
KDM4E B2RXH2 2/20 0.49
MAPK10 P53779 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29922938 1.00 ALDH1A1 (0.54) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL14230779 0.94 KMT2A (0.57) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL21368343 0.90 KDM4E (0.60) ALDH1A1HSD17B10KMT2AMAPTMEN1
SCHEMBL19335865 0.89 ALDH1A1 (0.44) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL349769 0.89 ALDH1A1 (0.55) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL30981854 0.89 IDO1 (0.50) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL29945563 0.86 HSD17B10 (0.48) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL7840881 0.84 P2RY12 (0.61) ALDH1A1TDP1KMT2AMAPTMEN1
SCHEMBL28771645 0.83 MAPT (0.62) ALDH1A1HSD17B10TSHRTDP1ALOX12
SCHEMBL24406180 0.82 AHR (0.55) ALDH1A1HSD17B10TSHRTDP1ALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115028626-B Thermally-induced delayed fluorescent material and preparation method and application thereof 西北工业大学 2023-10-17 CN disclosed
CN-115873025-A Condensed heterocyclic compound, application thereof and organic electroluminescent device containing compound 浙江虹舞科技有限公司 2023-03-31 CN disclosed
CN-115028626-A Thermally induced delayed fluorescent material and preparation method and application thereof 西北工业大学 2022-09-09 CN disclosed
CN-113461682-A Thermally induced delayed fluorescent material and preparation method and application thereof 西北工业大学 2021-10-01 CN disclosed
EP-2356168-B1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS SOLVAY USA INC (US) 2015-05-27 EP disclosed
EP-2356168-B1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS SOLVAY USA INC (US) 2015-05-27 EP disclosed
US-20130075670-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. (US) 2013-03-28 US disclosed
US-20130075670-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. (US) 2013-03-28 US disclosed
US-20130075670-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. (US) 2013-03-28 US disclosed
US-8283002-B2 Aminobenzene compositions and related devices and methods PLEXTRONICS, INC. (US) 2012-10-09 US disclosed
US-8283002-B2 Aminobenzene compositions and related devices and methods PLEXTRONICS, INC. (US) 2012-10-09 US disclosed
US-8283002-B2 Aminobenzene compositions and related devices and methods PLEXTRONICS, INC. (US) 2012-10-09 US disclosed
EP-2356168-A2 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS Plextronics, Inc. (US) 2011-08-17 EP disclosed
US-20100292399-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. 2010-11-18 US disclosed
US-20100292399-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. 2010-11-18 US disclosed
US-20100292399-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. 2010-11-18 US disclosed
WO-2010059646-A2 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. (US) 2010-05-27 WO disclosed
WO-2010059646-A2 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS PLEXTRONICS, INC. (US) 2010-05-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130075670-A1 AMINOBENZENE COMPOSITIONS AND RELATED DEVICES AND METHODS HLA-B, AAAS, SLCO2B1 ALDH1A1 2770/4885HSD17B10 2137/4885TSHR 4376/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.