SCHEMBL349769

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL28771645	0.95	MAPT (0.62)	ALDH1A1MAPTHTTALOX12L3MBTL1
	SCHEMBL8662787	0.91	KIF11 (0.46)	ALDH1A1MAPTHTTALOX12L3MBTL1
	SCHEMBL2332946	0.89	ALDH1A1 (0.54)	ALDH1A1MAPTHTTALOX12L3MBTL1
	SCHEMBL29922938	0.89	ALDH1A1 (0.54)	ALDH1A1MAPTHTTALOX12L3MBTL1
	SCHEMBL11097955	0.87	KMT2A (0.53)	ALDH1A1MAPTHTTALOX12L3MBTL1
	SCHEMBL14230779	0.84	KMT2A (0.57)	ALDH1A1MAPTALOX12L3MBTL1CYP3A4
	SCHEMBL21368343	0.80	KDM4E (0.60)	ALDH1A1MAPTHTTKMT2AGAA
	SCHEMBL30981854	0.80	IDO1 (0.50)	ALDH1A1MAPTALOX12L3MBTL1TDP1
	SCHEMBL19335865	0.80	ALDH1A1 (0.44)	ALDH1A1MAPTALOX12L3MBTL1CYP3A4
	SCHEMBL64307	0.78	PARP1 (0.61)	ALDH1A1MAPTKMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 266 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.