Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SDCBP | O00560 | 1/20 | 0.33 |
| ▸ | SDC2 | P34741 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15944431 | 0.83 | HPGD (0.42) | L3MBTL1ALDH1A1KMT2AMEN1NPC1 | |
| SCHEMBL11185069 | 0.81 | ALDH1A1 (0.43) | SMN1; SMN2MAOAALDH1A1KMT2AMEN1 | |
| SCHEMBL14234228 | 0.80 | DAO (0.41) | SMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3491068 | 0.75 | SMN1; SMN2 (0.46) | SMN1; SMN2MAOAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL8101750 | 0.73 | SMN1; SMN2 (0.49) | SMN1; SMN2MAOAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL10585292 | 0.73 | SMN1; SMN2 (0.49) | SMN1; SMN2MAOAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL6352969 | 0.71 | CA2 (0.45) | SMN1; SMN2L3MBTL1ALDH1A1NPC1RAB9A | |
| SCHEMBL7450074 | 0.71 | TSHR (0.46) | ALDH1A1KMT2AMEN1MAPTPOLB | |
| SCHEMBL10586257 | 0.70 | SMN1; SMN2 (0.42) | SMN1; SMN2MAOAL3MBTL1ALDH1A1KMT2A | |
| SCHEMBL17030474 | 0.70 | SMN1; SMN2 (0.48) | SMN1; SMN2MAOAL3MBTL1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021083209-A1 | SSAO INHIBITORS AND USE THEREOF | ECCOGENE (SHANGHAI) CO., LTD. (CN) | 2021-05-06 | — | — | WO | disclosed |