SCHEMBL2333180

SCHEMBL2333180

CCCCCCCCC[n+]1ccn(C)c1.F[B-](F)(F)F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CHRM2 P08172 2/20 0.44
▸ ADRA2A P08913 2/20 0.44
▸ ADORA3 P0DMS8 2/20 0.44
▸ CHRM1 P11229 2/20 0.44
▸ ACHE P22303 2/20 0.44
▸ SLC6A2 P23975 2/20 0.44
▸ SLC6A4 P31645 2/20 0.44
▸ SLC6A3 Q01959 2/20 0.44
▸ ABCB11 O95342 1/20 0.44
▸ ESR1 P03372 1/20 0.44
▸ PGR P06401 1/20 0.44
▸ HTR1A P08908 1/20 0.44
▸ DRD1 P21728 1/20 0.44
▸ TBXA2R P21731 1/20 0.44
▸ PTGS1 P23219 1/20 0.44
▸ PDE4A P27815 1/20 0.44
▸ ADRA1A P35348 1/20 0.44
▸ OPRM1 P35372 1/20 0.44
▸ DRD3 P35462 1/20 0.44
▸ KCNH2 Q12809 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17317394 1.00 CHRM2 (0.44) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL193365 1.00 CHRM2 (0.44) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL7749147 1.00 CHRM2 (0.44) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL385010 1.00 CHRM2 (0.44) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL18604185 1.00 CHRM2 (0.44) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL385721 1.00 CHRM2 (0.44) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL51478 1.00 CHRM2 (0.44) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL7065072 1.00 CHRM2 (0.44) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL2331938 1.00 CHRM2 (0.44) CHRM2ADRA2AADORA3CHRM1ACHE
SCHEMBL383271 1.00 CHRM2 (0.44) CHRM2ADRA2AADORA3CHRM1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8071080-B2 May be imidazolium, pyrazolium, pyridinium, pyrimidinium or tetraalkylphosphonium salts; washing (cleaning) and/or conditioning keratin materials, and especially the hair. L'OREAL (FR) 2011-12-06 — — US claimed
EP-1362572-B2 Use of at least one particular organic salt for cleansing and/or conditioning keratinous materials, use of a particular organic salt as conditioning agent for said materials and process for cosmetic treatment OREAL (FR) 2011-08-17 — — EP claimed
EP-1362572-B1 Use of at least one particular organic salt for cleansing and/or conditioning keratinous materials, use of a particular organic salt as conditioning agent for said materials and process for cosmetic treatment OREAL (FR) 2008-04-16 — — EP claimed
US-20040005286-A1 Organic salt conditioner, organic salt-containing composition, and uses thereof L'OREAL (FR) 2004-01-08 — — US claimed
US-12550617-B2 Piezoelectric composite materials having improved piezoelectric properties COMPAGNIE GENERALE DES ETABLISSEMENTS MICHELIN (FR) 2026-02-10 — — US disclosed
EP-4094304-B1 PIEZOELECTRIC COMPOSITE MATERIALS WITH IMPROVED PIEZOELECTRIC PROPERTIES MICHELIN & CIE (FR) 2025-04-16 — — EP disclosed
EP-3402486-B1 CCX168 FOR USE IN THE TREATMENT OF C3 GLOMERULOPATHY CHEMOCENTRYX INC (US) 2025-03-19 — — EP disclosed
EP-3474845-B1 IMMUNOMODULATOR COMPOUNDS CHEMOCENTRYX INC (US) 2024-03-20 — — EP disclosed
US-11793771-B2 Immunomodulator compounds CHEMOCENTRYX, INC. (US) 2023-10-24 — — US disclosed
US-11779576-B2 Method of treating C3 glomerulopathy CHEMOCENTRYX, INC. (US) 2023-10-10 — — US disclosed
US-20230117425-A1 IMMUNOMODULATOR COMPOUNDS CHEMOCENTRYX, INC. 2023-04-20 — — US disclosed
US-20230102258-A1 C5AR ANTAGONISTS CHEMOCENTRYX, INC. 2023-03-30 — — US disclosed
EP-2381778-A1 C5AR ANTAGONISTS ChemoCentryx, Inc. (US) 2011-11-02 — — EP disclosed
US-20100311753-A1 C5aR ANTAGONISTS CHEMOCENTRYX, INC. (US) 2010-12-09 — — US disclosed
WO-2010075257-A1 C5AR ANTAGONISTS CHEMOCENTRYX, INC. (US) 2010-07-01 — — WO disclosed
US-20100160320-A1 C5aR ANTAGONISTS CHEMOCENTRYX, INC. (US) 2010-06-24 — — US disclosed
US-20070112015-A1 Substituted dihydropyridines and methods of use CHEMOCENTRYX, INC. (US) 2007-05-17 — — US disclosed
WO-2007051062-A2 SUBSTITUTED DIHYDROPYRIDINES AND METHODS OF USE CHEMOCENTRYX, INC. (US) 2007-05-03 — — WO disclosed
US-20060110350-A1 Composition comprising electrophilic monomers and particular organic salts, and use thereof for cosmetic treatment of keratin materials L'OREAL S.A. (FR) 2006-05-25 — — US disclosed
US-20040005286-A1 Organic salt conditioner, organic salt-containing composition, and uses thereof L'OREAL (FR) 2004-01-08 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100160320-A1 C5aR ANTAGONISTS C5AR1, C5AR2, C3AR1 CHRM2 342/4885ADRA2A 190/4885ADORA3 121/4885
US-20230117425-A1 IMMUNOMODULATOR COMPOUNDS IL2, IL2RA, C3AR1 CHRM2 32/4885ADRA2A 97/4885ADORA3 278/4885
US-11779576-B2 Method of treating C3 glomerulopathy C3AR1, C5, C5AR1 CHRM2 1032/4885ADRA2A 1058/4885ADORA3 632/4885
US-20040005286-A1 Organic salt conditioner, organic salt-containing composition, and uses thereof KRT18, HCN4, PRKDC CHRM2 3434/4885ADRA2A 4852/4885ADORA3 2626/4885
US-11793771-B2 Immunomodulator compounds IL2, IL2RA, C3AR1 CHRM2 32/4885ADRA2A 97/4885ADORA3 278/4885
US-20230102258-A1 C5AR ANTAGONISTS C5AR1, C5AR2, C3AR1 CHRM2 342/4885ADRA2A 190/4885ADORA3 121/4885
US-20100311753-A1 C5aR ANTAGONISTS C5AR1, C5AR2, C3AR1 CHRM2 342/4885ADRA2A 190/4885ADORA3 121/4885
US-20070112015-A1 Substituted dihydropyridines and methods of use C3AR1, C5AR1, C5AR2 CHRM2 143/4885ADRA2A 171/4885ADORA3 77/4885
US-12550617-B2 Piezoelectric composite materials having improved piezoelectric properties PIEZO1, PIP5K1C, PIP5K1A CHRM2 1648/4885ADRA2A 1977/4885ADORA3 597/4885
US-20060110350-A1 Composition comprising electrophilic monomers and particular organic salts, and use thereof for cosmetic treatment of keratin materials KRT18, PRKDC, CUTA CHRM2 3142/4885ADRA2A 4746/4885ADORA3 4776/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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