SCHEMBL2333261

SCHEMBL2333261

Nc1ccc(-c2ccc(Br)cc2)cc1

nearest known ligand 0.81

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.81
MAPK1 P28482 2/20 0.81
ALOX15 P16050 1/20 0.81
CYP3A4 P08684 2/20 0.69
TDP1 Q9NUW8 2/20 0.69
TP53 P04637 2/20 0.69
MAPT P10636 5/20 0.59
HSD17B10 Q99714 2/20 0.55
TAAR1 Q96RJ0 2/20 0.55
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
CYP2A6 P11509 1/20 0.50
CA12 O43570 2/20 0.48
CA2 P00918 2/20 0.48
CA9 Q16790 2/20 0.48
KDM4E B2RXH2 2/20 0.46
KIF11 P52732 2/20 0.46
NPC1 O15118 2/20 0.44
RAB9A P51151 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
4-Bromoaniline SCHEMBL45481 0.90
4-Bromoaniline SCHEMBL22289673 0.87
4-Bromoaniline SCHEMBL2580141 0.87
4-Bromoaniline SCHEMBL9491015 0.87
4-Bromoaniline SCHEMBL28002358 0.87
4-Bromoaniline SCHEMBL4372833 0.87 ALDH1A1 (0.93) ALDH1A1MAPK1ALOX15CYP3A4TDP1
Biphenyl SCHEMBL27737435 0.86 ALDH1A1 (0.70) ALDH1A1MAPK1ALOX15CYP3A4TDP1
SCHEMBL28012604 0.85 ALDH1A1 (0.59) ALDH1A1MAPK1ALOX15CYP3A4TDP1
SCHEMBL28202311 0.85 ALDH1A1 (0.59) ALDH1A1MAPK1ALOX15CYP3A4TDP1
SCHEMBL68094 0.83 ALDH1A1 (0.73) ALDH1A1MAPK1ALOX15TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-57040429-A None JP disclosed
JP-56169633-A None JP disclosed
CN-115433457-B Nylon composite material with stable and compatible glass fibers and preparation method thereof 山东龙腾新材料有限公司 2023-08-22 CN disclosed
CN-115584126-B Ethylene glycol-resistant glass fiber reinforced PA66 thermoplastic composite material and preparation method thereof 山东龙腾新材料有限公司 2023-08-08 CN disclosed
US-20230107477-A1 LUMINESCENCE DEVICE AND AMINE COMPOUND FOR LUMINESCENCE DEVICE SAMSUNG DISPLAY CO LTD (KR) 2023-04-06 US disclosed
US-20230078029-A1 LUMINESCENCE DEVICE AND AMINE COMPOUND FOR LUMINESCENCE DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-03-16 US disclosed
CN-115584126-A Ethylene glycol-resistant glass fiber reinforced PA66 thermoplastic composite material and preparation method thereof 山东龙腾新材料有限公司 2023-01-10 CN disclosed
CN-115433457-A Nylon composite material with stable and compatible glass fibers and preparation method thereof 山东龙腾新材料有限公司 2022-12-06 CN disclosed
CN-109535422-B Diamine compound, polyimide film, and flexible display device 阜阳欣奕华材料科技有限公司 2021-08-24 CN disclosed
CN-108101896-B Organic electroluminescent compound, organic electroluminescent device and application thereof 南京高光半导体材料有限公司 2020-10-16 CN disclosed
WO-2006092429-A1 METHOD FOR PRODUCING SUBSTITUTED BIPHENYLS BASF AKTIENGESELLSCAHFT (DE) 2006-09-08 WO disclosed
US-5580741-A INCUBATING SAMPLE SOLUTION IN CONTAINER PRECOATED WITH ANTIBODY AND PROTEIN CONJUGATE YIELDS COMPLEXES, THEN REMOVAL AND REACTION WITH CHEMILUMINESCENT REAGENTS FOR MEASUREMENT OF LIGHT INTENSITY, FOR CHLORINATED BIPHENYLS GENERAL ELECTRIC COMPANY (US) 1996-12-03 US disclosed
EP-0263438-B1 BENZOYLUREA COMPOUNDS, PROCESS FOR THEIR PRODUCTION AND PESTICIDES CONTAINING THEM ISHIHARA SANGYO KAISHA, LTD. (JP) 1992-07-15 EP disclosed
US-4985449-A N-benzoyl-N-pyridyloxy phenyl urea compounds and pesticide compositions containing them ISHIHARA SANGYO KAISHA LTD. (JP) 1991-01-15 US disclosed
US-4861799-A INSSECTICIDES ISHIHARA SANGYO KAISHA LTD. (JP) 1989-08-29 US disclosed
US-4812548-A POLY(2-(4*-SUBSTITUTED-4-BIPHENYLOXY) ETHYL VINYL ETHERS) MITSUI CHEMICALS, INC. (JP) 1989-03-14 US disclosed
EP-0263438-A2 Benzoylurea compounds, process for their production and pesticides containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 1988-04-13 EP disclosed
JP-S5740429-A 4-(4-N-ALKYL-1-CYCLOHEXEN-1-YL)-4'-FLUOROBIPHENYL CHISSO CORP 1982-03-06 JP disclosed
JP-S56169633-A 4-(4-TRANS-N-ALKYLCYCLOHEXYL)-4'-FLUOROBIPHENYL CHISSO CORP 1981-12-26 JP disclosed
US-4154697-A Liquid crystalline hexahydroterphenyl derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 1979-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230107477-A1 LUMINESCENCE DEVICE AND AMINE COMPOUND FOR LUMINESCENCE DEVICE SLC18A1, SAT1, NAT1 ALDH1A1 60/4885MAPK1 1159/4885ALOX15 620/4885
US-20230078029-A1 LUMINESCENCE DEVICE AND AMINE COMPOUND FOR LUMINESCENCE DEVICE SLC18A1, SAT1, NAT1 ALDH1A1 53/4885MAPK1 1168/4885ALOX15 619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.