Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | PARG | Q86W56 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.39 |
| ▸ | FNTB | P49356 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | PTGDR | Q13258 | 4/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.37 |
| ▸ | PTGIR | P43119 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1189010 | 0.87 | F10 (0.54) | F10MEN1KMT2ATP53ALDH1A1 | |
| SCHEMBL2325323 | 0.83 | F10 (0.50) | F10 | |
| Trifluoroacetic Acid SCHEMBL2327044 | 0.78 | F10 (0.65) | F10 | |
| SCHEMBL6858450 | 0.73 | UCHL1 (0.50) | MEN1KMT2ATP53ALDH1A1HPGD | |
| SCHEMBL8425432 | 0.70 | SIRT2 (0.42) | F10SIRT2SIRT1ALDH1A1HPGD | |
| SCHEMBL651578 | 0.70 | FNTA (0.62) | F10THRBFNTAFNTBSIRT2 | |
| SCHEMBL6157745 | 0.69 | HCRTR1 (0.48) | HPGDTSHRCYP1A2CYP2C19CYP3A4 | |
| SCHEMBL650207 | 0.69 | FNTA (0.61) | F10THRBFNTAFNTBSIRT2 | |
| SCHEMBL7415513 | 0.68 | SIRT2 (0.51) | SIRT2SIRT1ALDH1A1HPGDTSHR | |
| SCHEMBL653291 | 0.67 | FNTA (0.57) | THRBFNTAFNTBSIRT2SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-B1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL -AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2011-08-17 | — | — | EP | disclosed |
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |