Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.42 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 2/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | CFD | P00746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8423834 | 0.70 | F10 (0.41) | SIRT2SIRT1ADRA1DJAK2JAK1 | |
| SCHEMBL2333283 | 0.70 | F10 (0.50) | SIRT2SIRT1L3MBTL1ALDH1A1HPGD | |
| SCHEMBL7415513 | 0.65 | SIRT2 (0.51) | SIRT2SIRT1ADRA1DL3MBTL1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL2332921 | 0.65 | SIRT2 (0.50) | SIRT2SIRT1ADRA1DL3MBTL1ALDH1A1 | |
| SCHEMBL2330939 | 0.62 | RORC (0.46) | SIRT2SIRT1L3MBTL1ALDH1A1 | |
| SCHEMBL2325323 | 0.62 | F10 (0.50) | F10 | |
| SCHEMBL7427081 | 0.62 | SIRT2 (0.60) | SIRT2SIRT1ADRA1DL3MBTL1ROCK2 | |
| SCHEMBL6157745 | 0.61 | HCRTR1 (0.48) | HPGD | |
| SCHEMBL2560664 | 0.59 | PDE10A (0.70) | L3MBTL1ALDH1A1PDE10AKDM4EHPGD | |
| SCHEMBL7427087 | 0.59 | SIRT2 (0.53) | SIRT2SIRT1ADRA1DL3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958918-A | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N- (aminominomethyl)phenylalkyl!-azaheterocyclylamide compounds | RHONE-POULENC RORER PHARMACEUTICALS INC. | 1999-09-28 | — | — | US | disclosed |