Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.36 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | METAP2 | P50579 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31478116 | 0.94 | NPC1 (0.39) | AAK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL4429420 | 0.84 | HSD11B1 (0.44) | MEN1KMT2ANPC1RAB9AKCNQ4 | |
| SCHEMBL31182208 | 0.82 | AAK1 (0.40) | AAK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL17873258 | 0.82 | AAK1 (0.40) | AAK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL17545325 | 0.81 | HSD11B1 (0.41) | NPC1RAB9ACYP17A1MAPTTHRB | |
| SCHEMBL29874295 | 0.80 | CYP17A1 (0.42) | AAK1RAB9AKCNQ4KCNQ5CYP17A1 | |
| SCHEMBL23334163 | 0.80 | DGAT1 (0.37) | AAK1KCNQ4KCNQ5CA12CA1 | |
| SCHEMBL24822119 | 0.79 | AAK1 (0.36) | AAK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL30050908 | 0.79 | AAK1 (0.36) | AAK1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL2952459 | 0.79 | RXFP1 (0.51) | MEN1KMT2ANPC1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021083182-A1 | URICOSURIC AGENT, SYNTHETIC METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 南京明德新药研发有限公司 | 2021-05-06 | — | — | WO | disclosed |