Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.39 |
| ▸ | NOS1 | P29475 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | STAT1 | P42224 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20448289 | 0.79 | ESR1 (0.35) | — | |
| SCHEMBL2326562 | 0.79 | CA1 (0.52) | MAPTRAB9AL3MBTL1KMT2ANPC1 | |
| SCHEMBL2329310 | 0.79 | ALDH1A1 (0.52) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL182327 | 0.78 | CYP2C9 (0.55) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL9683939 | 0.78 | MAPT (0.50) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL17319344 | 0.76 | MAPT (0.48) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL1262317 | 0.76 | MAPT (0.48) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL5197216 | 0.76 | CYP2C9 (0.53) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL16659380 | 0.75 | MAPT (0.52) | MAPTHPGDLMNARAB9AL3MBTL1 | |
| SCHEMBL19133292 | 0.74 | MAPT (0.46) | MAPTHPGDLMNARAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2133357-B1 | LIVING RADICAL POLYMERIZATION PROMOTER | OTSUKA CHEMICAL CO LTD (JP) | 2016-11-16 | — | — | EP | disclosed |
| US-8076430-B2 | Living radical polymerization promoter | OTSUKA CHEMICAL CO., LTD. (JP) | 2011-12-13 | — | — | US | disclosed |
| EP-1829883-B1 | ORGANIC BISMUTH COMPOUND, METHOD FOR PRODUCING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, METHOD FOR PRODUCING POLYMER USING SAME, AND POLYMER | OTSUKA CHEMICAL CO LTD (JP) | 2011-08-17 | — | — | EP | disclosed |
| US-7847043-B2 | Organic bismuth compound, method for producing same, living radical polymerization initiator, method for producing polymer using same, and polymer | OTSUKA CHEMICAL CO., LTD. (JP) | 2010-12-07 | — | — | US | disclosed |
| US-20100022728-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | OTSUKA CHEMICAL CO., LTD. (JP) | 2010-01-28 | — | — | US | disclosed |
| EP-2133357-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | Otsuka Chemical Holdings Co., Ltd. (JP) | 2009-12-16 | — | — | EP | disclosed |
| US-20070265404-A1 | Organic Bismuth Compound, Method for Producing Same, Living Radical Polymerization Initiator, Method for Producing Polymer Using Same, and Polymer | OTSUKA CHEMICAL CO., LTD. (JP) | 2007-11-15 | — | — | US | disclosed |
| EP-1829883-A1 | ORGANIC BISMUTH COMPOUND, METHOD FOR PRODUCING SAME, LIVING RADICAL POLYMERIZATION INITIATOR, METHOD FOR PRODUCING POLYMER USING SAME, AND POLYMER | Otsuka Chemical Co., Ltd. (JP) | 2007-09-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265404-A1 | Organic Bismuth Compound, Method for Producing Same, Living Radical Polymerization Initiator, Method for Producing Polymer Using Same, and Polymer | DOHH, COASY, ODC1 | MAPT 3794/4885HPGD 1763/4885LMNA 2747/4885 |
| US-20100022728-A1 | LIVING RADICAL POLYMERIZATION PROMOTER | DNMT1, CYP1B1, DNMT3B | MAPT 4496/4885HPGD 487/4885LMNA 2626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.