Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTPS1 | P17812 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23012256 | 0.89 | ALDH1A1 (0.39) | SLC6A3HPGDKDM4ENPC1MAPK1 | |
| SCHEMBL10148360 | 0.83 | DAO (0.55) | KDM4EALDH1A1MEN1KMT2ADAO | |
| SCHEMBL31322845 | 0.81 | HPGD (0.41) | SLC6A3HPGDKDM4ENPC1MAPK1 | |
| SCHEMBL23013340 | 0.74 | DAO (0.45) | KDM4EALDH1A1MEN1KMT2ADAO | |
| SCHEMBL20892550 | 0.73 | MRGPRX4 (0.43) | HPGDKDM4ENPC1MAPK1RAB9A | |
| SCHEMBL25172126 | 0.72 | MAPT (0.49) | HPGDKDM4ENPC1MAPK1RAB9A | |
| SCHEMBL31322638 | 0.72 | SLC6A3 (0.36) | SLC6A3HPGDKDM4ENPC1MAPK1 | |
| SCHEMBL23334343 | 0.72 | LCK (0.38) | SLC6A3SLC22A12 | |
| SCHEMBL25352809 | 0.70 | ALDH1A1 (0.42) | HPGDKDM4EMAPK1ALDH1A1MEN1 | |
| SCHEMBL7370288 | 0.70 | HPGD (0.41) | HPGDKDM4ENPC1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021083182-A1 | URICOSURIC AGENT, SYNTHETIC METHOD THEREFOR, AND PHARMACEUTICAL APPLICATION THEREOF | 南京明德新药研发有限公司 | 2021-05-06 | — | — | WO | disclosed |