SCHEMBL2333437

SCHEMBL2333437

Cc1ccc(N[N+](=O)[O-])cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.50
ALDH1A1 P00352 6/20 0.50
LMNA P02545 2/20 0.50
HSD17B10 Q99714 2/20 0.50
ACHE P22303 1/20 0.50
MEN1 O00255 4/20 0.43
KMT2A Q03164 4/20 0.43
HTT P42858 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
FBP1 P09467 1/20 0.42
TDP1 Q9NUW8 2/20 0.41
CYP3A4 P08684 2/20 0.41
HPGD P15428 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31732365 0.80 ALDH1A1 (0.38) MAPTALDH1A1LMNAHSD17B10MEN1
SCHEMBL10835888 0.76 MEN1 (0.43) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL2469875 0.76 ALDH1A1 (0.49) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL7078201 0.76 MAPT (0.49) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL30336 0.76 MAPT (0.47) MAPTALDH1A1LMNAHSD17B10MEN1
SCHEMBL4953735 0.76 ALDH1A1 (0.61) MAPTALDH1A1LMNAHSD17B10ACHE
SCHEMBL45336 0.76 ALDH1A1 (0.50) MAPTALDH1A1LMNAMEN1KMT2A
SCHEMBL3183983 0.76 MAPT (0.54) MAPTALDH1A1MEN1KMT2AHTT
SCHEMBL11567649 0.76 ENPP2 (0.45) MAPTLMNACA1CA2
SCHEMBL19745943 0.76 KMT2A (0.47) MAPTALDH1A1LMNAHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 168 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12209168-B2 Polyurethane foam premixes containing halogenated olefin blowing agents and foams made from same HONEYWELL INTERNATIONAL INC. (US) 2025-01-28 US claimed
CN-116019794-A Application of amino fullerene material in preparation of exosome PD-L1 inhibition drugs 中国科学院化学研究所 2023-04-28 CN claimed
CN-114272738-A Method for recycling nitrogen oxide gas in diazotization reaction process 南京理工大学 2022-04-05 CN claimed
CN-114249474-A Process for removing nitrophenol organic matters in wastewater 万华化学集团股份有限公司 2022-03-29 CN claimed
US-20210032430-A1 POLYURETHANE FOAM PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS AND FOAMS MADE FROM SAME SOLSTICE ADVANCED MATERIALS US, INC. 2021-02-04 US claimed
CN-109223828-A Application of amino fullerene in preparation of antibacterial material and antibacterial material 北京福纳康生物技术有限公司 2019-01-18 CN claimed
US-20180179358-A1 POLYURETHANE FOAM PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS AND FOAMS MADE FROM SAME YU BIN (US) 2018-06-28 US claimed
CN-106588692-A Method for improving diazotization reaction speed and conversion rate of weakly alkaline primary arylamine and application of method in synthesis of azo organic pigment 杭州荣彩实业有限公司 2017-04-26 CN claimed
CN-106494827-A One kind is used for putting damping type transmission equipment and its engineering philosophy in high flexibility mortar structure body 徐州工程学院 2017-03-15 CN claimed
US-20140171525-A1 POLYURETHANE FOAM PREMIXES CONTAINING HALOGENATED OLEFIN BLOWING AGENTS AND FOAMS MADE FROM SAME HONEYWELL INTERNATIONAL INC. (US) 2014-06-19 US claimed
US-4603216-A RUTHENIUM-PHOSPHINE CATALYST CATALYTICA ASSOCIATES (US) 1986-07-29 US claimed
US-4600793-A Process for the preparation of urethanes CATALYTICA ASSOCIATES (US) 1986-07-15 US claimed
EP-0157828-A1 PROCESS FOR THE PREPARATION OF URETHANES. CATALYTICA ASSOCIATES (US) 1985-10-16 EP claimed
WO-1985001285-A1 PROCESS FOR THE PREPARATION OF URETHANES CATALYTICA ASSOCIATES (US) 1985-03-28 WO claimed
EP-0000815-B1 PROCESS FOR PREPARING N-ARYL OR N-ARALKYL SUBSTITUTED URETHANES MITSUI TOATSU CHEMICALS, Inc. (JP) 1982-01-27 EP claimed
US-4227008-A CATALYTIC REACTION OF A NITRO-, NITROSO-, OR CARBAMATE-CONTAINING AROMATIC PRIMARY AMINE, AN ALCOHOL, AND CARBON MONOXIDE MITSUI TOATSU CHEMICALS, INCORPORATED (JP) 1980-10-07 US claimed
US-4159264-A Automatic control of azo coupling processes in the manufacture of azo pigments CIBA-GEIGY CORPORATION (US) 1979-06-26 US claimed
US-4151165-A USING AN AROMATIC NITRO COMPOUND IN OXYGEN-FREE, AQUEOUS ENVIRONMENT ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1979-04-24 US claimed
EP-0000815-A1 Process for preparing N-aryl or N-aralkyl substituted urethanes MITSUI TOATSU CHEMICALS, Inc. (JP) 1979-02-21 EP claimed
US-3990985-A Stable and storable aqueous dispersions of primary aromatic amines, their preparation and use HOECHST AKTIENGESELLSCHAFT (DT) 1976-11-09 US claimed