Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.70 |
| ▸ | GAA | P10253 | 3/20 | 0.56 |
| ▸ | ACHE | P22303 | 2/20 | 0.56 |
| ▸ | MGAM | O43451 | 1/20 | 0.56 |
| ▸ | SI | P14410 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 5/20 | 0.39 |
| ▸ | CA12 | O43570 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4785737 | 0.93 | MAOA (0.70) | MAOAGAAACHEMGAMSI | |
| SCHEMBL4785741 | 0.93 | MAOA (0.70) | MAOAGAAACHEMGAMSI | |
| SCHEMBL4744259 | 0.92 | MAOA (0.69) | MAOAGAAACHEMGAMSI | |
| SCHEMBL24756201 | 0.92 | MAOA (0.69) | MAOAGAAACHEMGAMSI | |
| SCHEMBL4744257 | 0.92 | MAOA (0.69) | MAOAGAAACHEMGAMSI | |
| Dihydropyranocoumarin D2 SCHEMBL4714194 | 0.92 | MAOA (0.72) | MAOAGAAACHEMGAMSI | |
| Dihydropyranocoumarin D2 SCHEMBL4714192 | 0.92 | MAOA (0.72) | MAOAGAAACHEMGAMSI | |
| Dihydropyranocoumarin D2 SCHEMBL14105795 | 0.92 | MAOA (0.72) | MAOAGAAACHEMGAMSI | |
| SCHEMBL23335044 | 0.91 | MAOA (0.68) | MAOAGAAACHEMGAMSI | |
| SCHEMBL31046711 | 0.90 | MAOA (0.67) | MAOAGAAACHEMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021086101-A1 | USE OF NOVEL COMPOUND, FOR PREVENTING, IMPROVING OR TREATING AMYOTROPHIC LATERAL SCLEROSIS | (주)피알지에스앤텍 | 2021-05-06 | — | — | WO | disclosed |