Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.69 |
| ▸ | ACHE | P22303 | 3/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | MGAM | O43451 | 1/20 | 0.55 |
| ▸ | SI | P14410 | 1/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.55 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 4/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 5/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4744257 | 1.00 | MAOA (0.69) | MAOAACHEGAAMGAMSI | |
| SCHEMBL4785737 | 0.92 | MAOA (0.70) | MAOAACHEGAAMGAMSI | |
| SCHEMBL23335041 | 0.92 | MAOA (0.70) | MAOAACHEGAAMGAMSI | |
| SCHEMBL4785741 | 0.92 | MAOA (0.70) | MAOAACHEGAAMGAMSI | |
| SCHEMBL24756833 | 0.91 | MAOA (0.67) | MAOAACHEGAAMGAMSI | |
| SCHEMBL24756201 | 0.91 | MAOA (0.69) | MAOAACHEGAAMGAMSI | |
| Dihydropyranocoumarin D2 SCHEMBL4714194 | 0.91 | MAOA (0.72) | MAOAACHEGAAMGAMSI | |
| Dihydropyranocoumarin D2 SCHEMBL14105795 | 0.91 | MAOA (0.72) | MAOAACHEGAAMGAMSI | |
| Dihydropyranocoumarin D2 SCHEMBL4714192 | 0.91 | MAOA (0.72) | MAOAACHEGAAMGAMSI | |
| SCHEMBL29933810 | 0.90 | MAOA (0.65) | MAOAACHEGAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008102994-A1 | COMPOSITION COMPRISING DECURSIN DERIVATIVE FOR TREATING AND PREVENTING ATOPIC DERMATITIS | PARK YONG JIN (KR) | 2008-08-28 | — | — | WO | claimed |
| US-7115655-B2 | Pyranocoumarin derivatives | ELCOM BIOTECHNOLOGY, CO. LTD. (KR) | 2006-10-03 | — | — | US | disclosed |
| US-20050222245-A1 | Pyranocoumarin derivatives | ELCOM BIOTECHNOLOGY, CO., LTD. (KR) | 2005-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222245-A1 | Pyranocoumarin derivatives | CYP3A5, GABRE, CUL1 | MAOA 1441/4885ACHE 144/4885GAA 1933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.