Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | METAP2 | P50579 | 3/20 | 0.31 |
| ▸ | METAP1 | P53582 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL23304739 | 0.98 | ALOX15 (0.32) | ALOX15ALDH1A1CYP2C9CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL23304740 | 0.98 | ALOX15 (0.32) | ALOX15ALDH1A1CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL1784949 | 0.81 | ALDH1A1 (0.42) | ALOX15ALDH1A1CYP2C9LMNAHSD17B10 | |
| SCHEMBL1784947 | 0.81 | ALDH1A1 (0.42) | ALOX15ALDH1A1CYP2C9LMNAHSD17B10 | |
| SCHEMBL29115603 | 0.80 | ALDH1A1 (0.37) | ALOX15ALDH1A1CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL29115601 | 0.80 | ALDH1A1 (0.37) | ALOX15ALDH1A1CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL23304648 | 0.80 | ALOX15 (0.37) | ALOX15ALDH1A1CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL23304647 | 0.80 | ALOX15 (0.37) | ALOX15ALDH1A1CYP2C9CYP2D6CYP2C19 | |
| SCHEMBL29115592 | 0.77 | ALDH1A1 (0.42) | ALOX15ALDH1A1CYP2C9LMNAHSD17B10 | |
| SCHEMBL30231620 | 0.77 | ALDH1A1 (0.42) | ALOX15ALDH1A1CYP2C9LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087018-A1 | PYRIDAZINONES AS PARP7 INHIBITORS | RIBON THERAPEUTICS, INC. (US) | 2021-05-06 | — | — | WO | disclosed |