Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 6/20 | 0.32 |
| ▸ | LCK | P06239 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23303632 | 0.82 | BTK (0.49) | BTKLCK | |
| SCHEMBL23303883 | 0.75 | BTK (0.54) | BTKLCK | |
| SCHEMBL23303943 | 0.73 | BTK (0.39) | BTKMAPT | |
| SCHEMBL23304198 | 0.72 | PRMT5 (0.38) | — | |
| SCHEMBL29840373 | 0.72 | PCSK9 (0.39) | BTK | |
| SCHEMBL23337481 | 0.72 | PCSK9 (0.39) | BTK | |
| SCHEMBL23303599 | 0.69 | BTK (0.46) | BTKLCK | |
| Trifluoroacetic Acid SCHEMBL31679713 | 0.66 | BTK (0.46) | BTKLCK | |
| SCHEMBL19891944 | 0.60 | BTK (0.51) | BTKLCK | |
| SCHEMBL23337486 | 0.59 | NPC1 (0.42) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021087112-A1 | CONDENSED BI-HETEROCYCLES AS INHIBITING AGENTS FOR BRUTON'S TYROSINE KINASE | BIOGEN MA INC. (US) | 2021-05-06 | — | — | WO | disclosed |