Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 20/20 | 0.51 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24426209 | 0.88 | BTK (0.56) | BTKLCK | |
| SCHEMBL24426191 | 0.87 | BTK (0.48) | BTKLCK | |
| SCHEMBL19876263 | 0.80 | BTK (0.60) | BTKLCK | |
| SCHEMBL23303632 | 0.79 | BTK (0.49) | BTKLCK | |
| SCHEMBL19891953 | 0.76 | BTK (0.47) | BTKLCK | |
| SCHEMBL22664846 | 0.75 | BTK (0.51) | BTKLCK | |
| SCHEMBL17645703 | 0.74 | BTK (0.46) | BTKLCK | |
| Hydrochloric Acid SCHEMBL22659441 | 0.74 | BTK (0.51) | BTKLCK | |
| Hydrochloric Acid SCHEMBL29533241 | 0.74 | BTK (0.51) | BTKLCK | |
| SCHEMBL29124814 | 0.74 | BTK (0.46) | BTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018035080-A1 | 2-OXO-IMIDAZOPYRIDINES AS REVERSIBLE BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2018-02-22 | — | — | WO | disclosed |