Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 8/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23337254 | 0.85 | HCAR2 (0.58) | RIPK1HCAR2KLKB1 | |
| SCHEMBL23219610 | 0.84 | ALPL (0.49) | RIPK1KLKB1 | |
| SCHEMBL19224520 | 0.79 | NR1H2 (0.56) | RIPK1HCAR2KLKB1 | |
| SCHEMBL24812993 | 0.75 | HDAC6 (0.46) | RIPK1HCAR2KLKB1 | |
| SCHEMBL21776198 | 0.73 | RIPK1 (0.50) | RIPK1 | |
| SCHEMBL29757046 | 0.73 | HCAR2 (0.50) | RIPK1HCAR2KLKB1 | |
| SCHEMBL25760819 | 0.71 | ALPL (0.43) | RIPK1KLKB1 | |
| SCHEMBL24193842 | 0.71 | ALPL (0.48) | RIPK1KLKB1 | |
| SCHEMBL24193687 | 0.71 | ALPL (0.48) | RIPK1KLKB1 | |
| SCHEMBL23337248 | 0.70 | HCAR2 (0.47) | RIPK1HCAR2KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3816163-A1 | CELL NECROSIS INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences (CN) | 2021-05-05 | — | — | EP | disclosed |