SCHEMBL23338686

SCHEMBL23338686

CC(C)c1cccc(C(C)C)c1N1C(=CC=C2C(=O)N(c3ccccc3)N(c3ccccc3)C2=O)N(c2c(C(C)C)cccc2C(C)C)c2nc3ccccc3nc21

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 4/20 0.38
NR1H2 P55055 1/20 0.38
NR1H3 Q13133 1/20 0.38
ANPEP P15144 4/20 0.34
NR1H4 Q96RI1 1/20 0.31
ALDH1A1 P00352 2/20 0.30
MAPT P10636 2/20 0.30
HTT P42858 2/20 0.30
SMN1; SMN2 Q16637 2/20 0.30
LMNA P02545 1/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
KDM4E B2RXH2 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25849580 0.94 DPP4 (0.36) DPP4NR1H2NR1H3ANPEP
SCHEMBL26300124 0.85 DPP4 (0.39) DPP4NR1H2NR1H3ANPEPALDH1A1
SCHEMBL23337591 0.81 DPP4 (0.39) DPP4NR1H2NR1H3ANPEPALDH1A1
SCHEMBL23337880 0.81 DPP4 (0.36) DPP4NR1H2NR1H3ANPEPALDH1A1
SCHEMBL23337853 0.80 DPP4 (0.36) DPP4NR1H2NR1H3ANPEPALDH1A1
SCHEMBL25849586 0.79 DPP4 (0.41) DPP4NR1H2NR1H3ANPEPALDH1A1
SCHEMBL25849822 0.78 ELANE (0.39) DPP4NR1H2NR1H3ANPEPALDH1A1
SCHEMBL25165376 0.78 KMT2A (0.34) DPP4NR1H2NR1H3ALDH1A1MAPT
SCHEMBL25850922 0.78 ANPEP (0.37) DPP4NR1H2NR1H3ANPEPMAPT
SCHEMBL23337546 0.77 DPP4 (0.42) DPP4NR1H2NR1H3ANPEPALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210135128-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2021-05-06 US disclosed