Sugi Predict

Sugi Predict / Compounds / SCHEMBL25850922

SCHEMBL25850922

SCHEMBL25850922

Bc1ccc2c(c1)C(=O)/C(=C/C=C1N(c3c(C(C)C)cccc3C(C)C)c3nc4ccccc4nc3N1c1c(C(C)C)cccc1C(C)C)C2=O

nearest known ligand 0.37

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ ANPEP P15144 4/20 0.37
▸ DPP4 P27487 4/20 0.37
▸ NR1H2 P55055 1/20 0.36
▸ NR1H3 Q13133 1/20 0.36
▸ MEN1 O00255 1/20 0.30
▸ MAPT P10636 1/20 0.30
▸ APEX1 P27695 1/20 0.30
▸ KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25850974 0.92 ANPEP (0.36) ANPEPDPP4NR1H2NR1H3
SCHEMBL25850932 0.89 ANPEP (0.33) ANPEPDPP4NR1H2NR1H3
SCHEMBL23337591 0.89 DPP4 (0.39) ANPEPDPP4NR1H2NR1H3MEN1
SCHEMBL25850997 0.89 TP53 (0.39) ANPEPDPP4MEN1MAPTKMT2A
SCHEMBL25849822 0.88 ELANE (0.39) ANPEPDPP4NR1H2NR1H3MEN1
SCHEMBL25850983 0.88 ANPEP (0.33) ANPEPDPP4NR1H2NR1H3
SCHEMBL25850960 0.87 ANPEP (0.39) ANPEPDPP4NR1H2NR1H3
SCHEMBL25851011 0.87 MAPT (0.33) ANPEPDPP4MEN1MAPTAPEX1
SCHEMBL23337546 0.84 DPP4 (0.42) ANPEPDPP4NR1H2NR1H3MEN1
SCHEMBL25849554 0.83 DPP4 (0.36) ANPEPDPP4NR1H2NR1H3MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230232713-A1 PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, OPTICAL SENSOR, AND COMPOUND FUJIFILM CORPORATION (JP) 2023-07-20 — — US disclosed