Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 9/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.45 |
| ▸ | RBP4 | P02753 | 2/20 | 0.39 |
| ▸ | EP300 | Q09472 | 8/20 | 0.39 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.39 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16118428 | 0.83 | CREBBP (0.47) | CREBBPBRD4RBP4EP300DPP4 | |
| SCHEMBL17229703 | 0.83 | CREBBP (0.47) | CREBBPBRD4RBP4EP300DPP4 | |
| SCHEMBL19413418 | 0.81 | CREBBP (0.48) | CREBBPBRD4RBP4EP300DPP4 | |
| SCHEMBL24727762 | 0.78 | CREBBP (0.43) | CREBBPBRD4RBP4EP300MAPK1 | |
| SCHEMBL17229710 | 0.77 | RBP4 (0.46) | CREBBPBRD4RBP4EP300DPP4 | |
| SCHEMBL20696228 | 0.76 | CREBBP (0.42) | CREBBPBRD4RBP4EP300DPP4 | |
| SCHEMBL17465959 | 0.76 | CREBBP (0.40) | CREBBPBRD4RBP4EP300DPP4 | |
| SCHEMBL17518081 | 0.76 | CREBBP (0.40) | CREBBPBRD4RBP4EP300DPP4 | |
| SCHEMBL17232732 | 0.75 | RBP4 (0.47) | CREBBPBRD4RBP4EP300DPP4 | |
| SCHEMBL20952900 | 0.74 | CREBBP (0.41) | CREBBPBRD4RBP4EP300DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3495357-B1 | 4-PHENYLPIPERIDINES, THEIR PREPARATION AND USE | UNIV COLUMBIA (US) | 2021-05-05 | — | — | EP | disclosed |