Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | DPP4 | P27487 | 14/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3917383 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GAANPSR1NPC1MAPT | |
| SCHEMBL296011 | 0.82 | ALDH1A1 (0.47) | ALDH1A1GAANPSR1NPC1MAPT | |
| SCHEMBL1234256 | 0.80 | ALDH1A1 (0.48) | ALDH1A1GAANPSR1NPC1MAPT | |
| SCHEMBL6545328 | 0.79 | ALDH1A1 (0.44) | ALDH1A1GAANPSR1NPC1MAPT | |
| SCHEMBL27573216 | 0.79 | ALDH1A1 (0.47) | ALDH1A1GAADPP4NPSR1NPC1 | |
| Acetic Acid SCHEMBL27819914 | 0.78 | ALDH1A1 (0.43) | ALDH1A1GAANPSR1NPC1MAPT | |
| SCHEMBL21107395 | 0.78 | ALDH1A1 (0.48) | ALDH1A1DPP4NPSR1 | |
| SCHEMBL1320791 | 0.78 | ALDH1A1 (0.48) | ALDH1A1DPP4NPSR1 | |
| SCHEMBL6870669 | 0.78 | ALDH1A1 (0.45) | ALDH1A1GAANPSR1NPC1MAPT | |
| SCHEMBL6545168 | 0.77 | ALDH1A1 (0.46) | ALDH1A1GAANPSR1NPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210130411-A1 | CYCLIC HEXAPEPTIDES COMPOUNDS WITH ANTI-MALARIAL ACTIVITY | UNIVERSIDAD DE LA REPÚBLICA (UDELAR) (UY) | 2021-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210130411-A1 | CYCLIC HEXAPEPTIDES COMPOUNDS WITH ANTI-MALARIAL ACTIVITY | VIP, NGLY1, HAMP | ALDH1A1 4645/4885GAA 1224/4885DPP4 265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.