Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 6/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2327211 | 0.81 | KMT2A (0.47) | KMT2AALDH1A1LMNAL3MBTL1GAA | |
| SCHEMBL13310957 | 0.80 | ALDH1A1 (0.55) | KMT2AALDH1A1LMNAL3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL2332778 | 0.78 | KMT2A (0.62) | KMT2AALDH1A1LMNAL3MBTL1GAA | |
| SCHEMBL12445241 | 0.78 | ALDH1A1 (0.50) | KMT2AALDH1A1LMNAL3MBTL1GAA | |
| SCHEMBL13310961 | 0.77 | KMT2A (0.46) | KMT2AALDH1A1LMNAL3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL2330352 | 0.77 | KMT2A (0.69) | KMT2AALDH1A1LMNAL3MBTL1GAA | |
| Hydrochloric Acid SCHEMBL2330965 | 0.76 | KMT2A (0.71) | KMT2AALDH1A1LMNAL3MBTL1GAA | |
| SCHEMBL13347784 | 0.75 | KMT2A (0.42) | KMT2AALDH1A1LMNAL3MBTL1GAA | |
| SCHEMBL13310979 | 0.75 | KMT2A (0.63) | KMT2AALDH1A1LMNAL3MBTL1GAA | |
| SCHEMBL2333441 | 0.74 | S1PR2 (0.61) | KMT2AALDH1A1LMNAL3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011097600-A1 | SCREENING METHOD AND COMPOUNDS FOR MODULATING TELOMERASE ACTIVITY | THE WISTAR INSTITUTE (US) | 2011-08-11 | — | — | WO | disclosed |