Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP1LC3B | Q9GZQ8 | 6/20 | 0.58 |
| ▸ | CRBN | Q96SW2 | 10/20 | 0.56 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.55 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.55 |
| ▸ | IKZF1 | Q13422 | 2/20 | 0.55 |
| ▸ | BRD4 | O60885 | 1/20 | 0.55 |
| ▸ | TNF | P01375 | 1/20 | 0.55 |
| ▸ | IL1B | P01584 | 1/20 | 0.55 |
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.48 |
| ▸ | AXL | P30530 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30437876 | 0.97 | MAP1LC3B (0.57) | MAP1LC3BCRBNIKZF3DDB1IKZF1 | |
| SCHEMBL28339018 | 0.96 | MAP1LC3B (0.56) | MAP1LC3BCRBNIKZF3DDB1IKZF1 | |
| SCHEMBL21596993 | 0.96 | MAP1LC3B (0.56) | MAP1LC3BCRBNIKZF3DDB1IKZF1 | |
| SCHEMBL30437987 | 0.96 | MAP1LC3B (0.56) | MAP1LC3BCRBNIKZF3DDB1IKZF1 | |
| SCHEMBL30438159 | 0.96 | MAP1LC3B (0.56) | MAP1LC3BCRBNIKZF3DDB1IKZF1 | |
| SCHEMBL30438144 | 0.96 | MAP1LC3B (0.56) | MAP1LC3BCRBNIKZF3DDB1IKZF1 | |
| SCHEMBL30438106 | 0.94 | MAP1LC3B (0.62) | MAP1LC3BCRBNIKZF3DDB1IKZF1 | |
| SCHEMBL28341506 | 0.94 | MAP1LC3B (0.62) | MAP1LC3BCRBNIKZF3DDB1IKZF1 | |
| SCHEMBL30438110 | 0.89 | STAT3 (0.59) | MAP1LC3BCRBNIKZF3DDB1IKZF1 | |
| SCHEMBL28339366 | 0.89 | STAT3 (0.59) | MAP1LC3BCRBNIKZF3DDB1IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110615779-B | Process for preparing lenalidomide derivatives | 上海科技大学 | 2023-03-24 | — | — | CN | claimed |
| WO-2021086069-A1 | COMPOUND COMPRISING EZH2 INHIBITOR AND E3 LIGASE BINDER AND PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING EZH2-ASSOCIATED DISEASE COMPRISING SAME AS ACTIVE INGREDIENT | 재단법인 대구경북첨단의료산업진흥재단 | 2021-05-06 | — | — | WO | disclosed |