SCHEMBL28339366

SCHEMBL28339366

[N-]=[N+]=NCCOCCNc1cccc2c1CN(C1CCC(=O)NC1=O)C2=O

nearest known ligand 0.59

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ STAT3 P40763 1/20 0.59
▸ MAP1LC3B Q9GZQ8 8/20 0.57
▸ CRBN Q96SW2 7/20 0.52
▸ IKZF3 Q9UKT9 5/20 0.52
▸ DDB1 Q16531 2/20 0.52
▸ IKZF1 Q13422 2/20 0.52
▸ TNF P01375 2/20 0.52
▸ BRD4 O60885 1/20 0.52
▸ IL1B P01584 1/20 0.52
▸ CSNK1A1 P48729 3/20 0.46
▸ GSPT1 P15170 2/20 0.45
▸ SALL4 Q9UJQ4 2/20 0.45
▸ HDAC3 O15379 1/20 0.45
▸ HDAC1 Q13547 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30438110 1.00 STAT3 (0.59) STAT3MAP1LC3BCRBNIKZF3DDB1
SCHEMBL30437666 0.99 STAT3 (0.60) STAT3MAP1LC3BCRBNIKZF3DDB1
SCHEMBL30437668 0.99 STAT3 (0.60) STAT3MAP1LC3BCRBNIKZF3DDB1
SCHEMBL28341501 0.99 STAT3 (0.60) STAT3MAP1LC3BCRBNIKZF3DDB1
SCHEMBL30438101 0.99 STAT3 (0.60) STAT3MAP1LC3BCRBNIKZF3DDB1
SCHEMBL28341506 0.91 MAP1LC3B (0.62) STAT3MAP1LC3BCRBNIKZF3DDB1
SCHEMBL30438106 0.91 MAP1LC3B (0.62) STAT3MAP1LC3BCRBNIKZF3DDB1
SCHEMBL23343050 0.89 MAP1LC3B (0.58) STAT3MAP1LC3BCRBNIKZF3DDB1
SCHEMBL17536588 0.89 STAT3 (0.66) STAT3MAP1LC3BCRBNIKZF3DDB1
SCHEMBL30437876 0.89 MAP1LC3B (0.57) STAT3MAP1LC3BCRBNIKZF3DDB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110615779-B Process for preparing lenalidomide derivatives 上海科技大学 2023-03-24 — — CN claimed
CN-110615779-A Process for preparing lenalidomide derivatives 上海科技大学 2019-12-27 — — CN claimed
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