Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP | O00591 | 2/20 | 0.47 |
| ▸ | GABRD | O14764 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.47 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.47 |
| ▸ | GABRE | P78334 | 2/20 | 0.47 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.47 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.47 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.47 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.42 |
| ▸ | DPP4 | P27487 | 4/20 | 0.37 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.34 |
| ▸ | KDM4A | O75164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23470297 | 0.78 | TET2 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2802126 | 0.78 | TET2 (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL7141671 | 0.75 | GABRP (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL23470298 | 0.73 | CYP1A2 (0.39) | CYP1A2DPP4MAPK1MAOB | |
| SCHEMBL20963089 | 0.71 | DPP4 (0.41) | CYP1A2DPP4MAPK1SLC1A2MAOB | |
| SCHEMBL869340 | 0.71 | DPP4 (0.41) | CYP1A2DPP4MAPK1SLC1A2MAOB | |
| SCHEMBL247201 | 0.70 | CHRNB2 (0.54) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL8534651 | 0.69 | GABRP (0.46) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL19614398 | 0.69 | DPP4 (0.40) | CYP1A2DPP4MAPK1MAOB | |
| SCHEMBL2801082 | 0.69 | SLC1A2 (0.35) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3268348-B1 | PROCESS FOR MAKING MIXTURES OF ENANTIOMERS, AND MIXTURES OF ENANTIOMERS | BASF SE (DE) | 2021-05-12 | — | — | EP | disclosed |