SCHEMBL2334449

SCHEMBL2334449

CSCC[C@H](NC(=O)c1ccccc1C(C)=O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FNTA P49354 4/20 0.55
FNTB P49356 4/20 0.55
ALDH1A1 P00352 2/20 0.55
NPSR1 Q6W5P4 1/20 0.55
PGGT1B P53609 1/20 0.53
TDP1 Q9NUW8 1/20 0.53
CA2 P00918 2/20 0.53
CA1 P00915 1/20 0.53
USP2 O75604 1/20 0.53
TSHR P16473 1/20 0.53
GAA P10253 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2334454 1.00 FNTA (0.55) FNTAFNTBALDH1A1NPSR1PGGT1B
SCHEMBL2329886 0.90 ALDH1A1 (0.56) FNTAFNTBALDH1A1NPSR1PGGT1B
SCHEMBL2329890 0.90 ALDH1A1 (0.56) FNTAFNTBALDH1A1NPSR1PGGT1B
SCHEMBL2327397 0.86 ALDH1A1 (0.53) FNTAFNTBALDH1A1NPSR1CA2
SCHEMBL2326573 0.86 ALDH1A1 (0.53) FNTAFNTBALDH1A1NPSR1PGGT1B
SCHEMBL2327402 0.86 ALDH1A1 (0.53) FNTAFNTBALDH1A1NPSR1CA2
SCHEMBL2326569 0.86 ALDH1A1 (0.53) FNTAFNTBALDH1A1NPSR1PGGT1B
SCHEMBL2330092 0.86 FPR1 (0.57) FNTAFNTBALDH1A1NPSR1CA2
SCHEMBL2330087 0.86 FPR1 (0.57) FNTAFNTBALDH1A1NPSR1CA2
SCHEMBL2330953 0.85 ALDH1A1 (0.54) FNTAFNTBALDH1A1NPSR1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2356979-B1 ANTI-WRINKLE AGENTS POLA CHEM IND INC (JP) 2017-10-25 EP disclosed
EP-3173063-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2017-05-31 EP disclosed
US-8835498-B2 Anti-wrinkle agents POLA CHEMICAL INDUSTRIES INC. (JP) 2014-09-16 US disclosed
US-20110245343-A1 ANTI-WRINKLE AGENTS POLA CHEMICAL INDUSTRIES INC. (JP) 2011-10-06 US disclosed
EP-2356979-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2011-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245343-A1 ANTI-WRINKLE AGENTS GLA, H1-4, H1-3 FNTA 4644/4885FNTB 4431/4885ALDH1A1 2655/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.