Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CTSD | P07339 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.45 |
| ▸ | ITGAV | P06756 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2334217 | 0.91 | TAS1R3 (0.44) | HPGDALDH1A1CTSDTAS1R3TAS1R1 | |
| SCHEMBL2327761 | 0.90 | HPGD (0.50) | HPGDALDH1A1CTSDTP53GLA | |
| SCHEMBL2326117 | 0.88 | HCRTR1 (0.52) | HPGDALDH1A1RAB9ATSHRKMT2A | |
| SCHEMBL2334202 | 0.87 | HPGD (0.56) | HPGDALDH1A1CTSDTP53GLA | |
| SCHEMBL2334197 | 0.87 | HPGD (0.56) | HPGDALDH1A1CTSDTP53GLA | |
| SCHEMBL2328285 | 0.87 | TAS1R3 (0.47) | HPGDALDH1A1CTSDTP53GLA | |
| SCHEMBL2327704 | 0.87 | MEN1 (0.50) | ALDH1A1TP53KMT2A | |
| SCHEMBL2330438 | 0.86 | KMT2A (0.46) | ALDH1A1TSHRKMT2ALMNA | |
| SCHEMBL2330575 | 0.86 | ALDH1A1 (0.50) | HPGDALDH1A1CTSDTP53GLA | |
| SCHEMBL2324537 | 0.86 | ALDH1A1 (0.53) | ALDH1A1TP53TSHRKMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356979-B1 | ANTI-WRINKLE AGENTS | POLA CHEM IND INC (JP) | 2017-10-25 | — | — | EP | disclosed |
| EP-2524686-B1 | PIGMENTATION-PREVENTING OR -AMELIORATING AGENT | POLA CHEM IND INC (JP) | 2017-06-21 | — | — | EP | disclosed |
| EP-3173063-A1 | ANTI-WRINKLE AGENTS | Pola Chemical Industries Inc. (JP) | 2017-05-31 | — | — | EP | disclosed |
| US-9066914-B2 | Prophylactic or ameliorating agent for pigmentation | POLA CHEMICAL INDUSTRIES INC. (JP) | 2015-06-30 | — | — | US | disclosed |
| US-8835498-B2 | Anti-wrinkle agents | POLA CHEMICAL INDUSTRIES INC. (JP) | 2014-09-16 | — | — | US | disclosed |
| EP-2524686-A1 | PIGMENTATION-PREVENTING OR -AMELIORATING AGENT | Pola Chemical Industries Inc. (JP) | 2012-11-21 | — | — | EP | disclosed |
| US-20120282203-A1 | PROPHYLACTIC OR AMELIORATING AGENT FOR PIGMENTATION | POLA CHEMICAL INDUSTRIES INC. (JP) | 2012-11-08 | — | — | US | disclosed |
| US-20110245343-A1 | ANTI-WRINKLE AGENTS | POLA CHEMICAL INDUSTRIES INC. (JP) | 2011-10-06 | — | — | US | disclosed |
| EP-2356979-A1 | ANTI-WRINKLE AGENTS | Pola Chemical Industries Inc. (JP) | 2011-08-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120282203-A1 | PROPHYLACTIC OR AMELIORATING AGENT FOR PIGMENTATION | TYR, MC1R, NQO1 | HPGD 250/4885ALDH1A1 136/4885CTSD 4574/4885 |
| US-20110245343-A1 | ANTI-WRINKLE AGENTS | GLA, H1-4, H1-3 | HPGD 1394/4885ALDH1A1 2655/4885CTSD 3604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.