SCHEMBL2334528

SCHEMBL2334528

Cc1cc(=O)oc2cc(NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](NC(=O)[C@H](CO)NC(=O)[C@H](CC(C)C)NC(=O)OC(C)(C)C)[C@@H](C)O)ccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA9 Q16790 1/20 0.45
MAP1LC3B Q9GZQ8 1/20 0.42
MAP1LC3A Q9H492 1/20 0.42
RAB9A P51151 3/20 0.38
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 3/20 0.38
HPGD P15428 3/20 0.38
NPC1 O15118 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
NPY4R P50391 7/20 0.38
NPY1R P25929 5/20 0.37
NPY5R Q15761 4/20 0.37
NPY2R P49146 3/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29419661 0.93 CA12 (0.52) CA12CA1CA9MAP1LC3BMAP1LC3A
SCHEMBL17821546 0.93 CA12 (0.52) CA12CA1CA9MAP1LC3BMAP1LC3A
SCHEMBL2199089 0.93 CA12 (0.52) CA12CA1CA9MAP1LC3BMAP1LC3A
Hydrochloric Acid SCHEMBL11217796 0.90 CA1 (0.49) CA12CA1CA9MAP1LC3BMAP1LC3A
SCHEMBL6916459 0.90 CA1 (0.51) CA12CA1CA9MAP1LC3BMAP1LC3A
SCHEMBL29543720 0.90 CA1 (0.51) CA12CA1CA9MAP1LC3BMAP1LC3A
Acetic Acid SCHEMBL29692755 0.88 CA1 (0.49) CA12CA1CA9MAP1LC3BMAP1LC3A
SCHEMBL14050068 0.88 CA12 (0.49) CA12CA1CA9MAP1LC3BMAP1LC3A
SCHEMBL29405051 0.88 CA12 (0.49) CA12CA1CA9MAP1LC3BMAP1LC3A
SCHEMBL29543787 0.87 CA1 (0.53) CA12CA1CA9MAP1LC3BMAP1LC3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1372598-B1 USE OF A PHAEODACTYLUM ALGAE EXTRACT TO PROMOTE THE PROTEASOME ACTIVITY OF SKIN CELLS LVMH RECH (FR) 2011-08-17 EP disclosed
US-7220417-B2 Use of phaeodactylum algae extract as cosmetic agent promoting the proteasome activity of skin cells and cosmetic composition comprising same LVMH RECHERCHE (FR) 2007-05-22 US disclosed
CN-1237979-C Use of phaeodactylum algae extract to promote proteasome activity of skin cells LVMH RECH (FR) 2006-01-25 CN disclosed