Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA12 | O43570 | 2/20 | 0.51 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6916459 | 1.00 | CA1 (0.51) | CA1CA12CA9KDM4EALDH1A1 | |
| Acetic Acid SCHEMBL29692755 | 0.98 | CA1 (0.49) | CA1CA12CA9KDM4EALDH1A1 | |
| SCHEMBL29543787 | 0.97 | CA1 (0.53) | CA1CA12CA9KDM4EALDH1A1 | |
| SCHEMBL2199089 | 0.92 | CA12 (0.52) | CA1CA12CA9KDM4EALDH1A1 | |
| SCHEMBL29419661 | 0.92 | CA12 (0.52) | CA1CA12CA9KDM4EALDH1A1 | |
| SCHEMBL17821546 | 0.92 | CA12 (0.52) | CA1CA12CA9KDM4EALDH1A1 | |
| SCHEMBL29543863 | 0.91 | CA1 (0.53) | CA1CA12CA9KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL11350984 | 0.90 | CA1 (0.46) | CA1CA12CA9KDM4EALDH1A1 | |
| SCHEMBL4817548 | 0.90 | TDP1 (0.47) | CA1CA12CA9KDM4EALDH1A1 | |
| SCHEMBL2334528 | 0.90 | CA12 (0.45) | CA1CA12CA9KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12208107-B2 | Method and compositions for the treatment of anemia through the inhibition of furin | BRIGHAM YOUNG UNIVERSITY (US) | 2025-01-28 | — | — | US | disclosed |
| US-11851697-B2 | Ex vivo protease activity detection for disease detection/diagnostic, staging, monitoring and treatment | GLYMPSE BIO, INC. (US) | 2023-12-26 | — | — | US | disclosed |
| US-20230038724-A1 | METHOD AND COMPOSITIONS FOR THE TREATMENT OF ANEMIA THROUGH THE INHIBITION OF FURIN | BRIGHAM YOUNG UNIVERSITY | 2023-02-09 | — | — | US | disclosed |
| US-11458148-B2 | Method and compositions for the treatment of anemia through the inhibition of furin | BRIGHAM YOUNG UNIVERSITY (US) | 2022-10-04 | — | — | US | disclosed |
| US-20220128546-A1 | EX VIVO PROTEASE ACTIVITY DETECTION FOR DISEASE DETECTION/DIAGNOSTIC, STAGING, MONITORING AND TREATMENT | Sunbird Bio, Inc. | 2022-04-28 | — | — | US | disclosed |