Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.59 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.59 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | DUT | P33316 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5325743 | 0.79 | CRBN (0.66) | CRBNDDB1PKMHCAR1 | |
| SCHEMBL21995599 | 0.76 | CRBN (0.66) | CRBNDDB1PKMHCAR1KMT2A | |
| SCHEMBL25207533 | 0.76 | CRBN (0.66) | CRBNDDB1PKMMEN1KMT2A | |
| SCHEMBL23120610 | 0.76 | CRBN (0.66) | CRBNDDB1PKMHCAR1KMT2A | |
| SCHEMBL26096140 | 0.76 | CRBN (0.66) | CRBNDDB1HCAR1CA1CA2 | |
| SCHEMBL28744560 | 0.75 | CRBN (0.59) | CRBNDDB1PKMHCAR1ATM | |
| SCHEMBL5289086 | 0.75 | CRBN (0.59) | CRBNDDB1PKMHCAR1ATM | |
| SCHEMBL25565834 | 0.75 | CRBN (0.59) | CRBNDDB1PKMMEN1KMT2A | |
| SCHEMBL1530734 | 0.75 | CRBN (1.00) | CRBNDDB1HCAR1ATMDUT | |
| SCHEMBL23345942 | 0.75 | PKM (0.43) | PKMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3819006-A1 | COMPOUNDS WITH THYMINE SKELETON FOR USE IN MEDICINE | Technische Universität Dresden (DE) | 2021-05-12 | — | — | EP | disclosed |