Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | TP53 | P04637 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 7/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12668533 | 0.92 | ALDH1A1 (0.56) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL39816 | 0.92 | THRB (0.74) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL15082554 | 0.90 | THRB (0.72) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL238953 | 0.86 | THRB (0.70) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL29516228 | 0.85 | ALDH1A1 (0.68) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL13779722 | 0.85 | THRB (0.66) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL5866608 | 0.85 | ALDH1A1 (0.68) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL19659608 | 0.85 | THRB (0.66) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL28389145 | 0.85 | ALDH1A1 (0.68) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL106268 | 0.85 | THRB (0.60) | THRBALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139711-A1 | THERMOFORMABLE AND SCRATCH-RESISTANT PHOTOPOLYMER COATINGS | ARKEMA FRANCE (FR) | 2021-05-13 | — | — | US | disclosed |