SCHEMBL23346265

SCHEMBL23346265

O=C(O)c1cc(C#Cc2cc(C#Cc3cc(C(=O)O)cc(C(=O)O)c3)cc(C#Cc3cc(C(=O)O)cc(C(=O)O)c3)c2)cc(C(=O)O)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.46
CA1 P00915 3/20 0.46
CA2 P00918 3/20 0.46
CA7 P43166 3/20 0.46
CA9 Q16790 3/20 0.46
CA14 Q9ULX7 3/20 0.46
LCK P06239 1/20 0.44
FYN P06241 1/20 0.44
TPMT P51580 3/20 0.44
TP53 P04637 2/20 0.44
CA3 P07451 2/20 0.44
CA4 P22748 2/20 0.44
CA6 P23280 2/20 0.44
CA5A P35218 2/20 0.44
CA5B Q9Y2D0 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
MAPT P10636 1/20 0.44
SELL P14151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16749633 0.97 CA12 (0.48) CA12CA1CA2CA7CA9
SCHEMBL18604545 0.93 RARB (0.50) CA12CA1CA2CA7CA9
SCHEMBL15521778 0.93 DHODH (0.41) CA12CA1CA2CA7CA9
SCHEMBL17354772 0.90 CA12 (0.42) CA12CA1CA2CA7CA9
SCHEMBL29908913 0.89 HNF4A (0.46) CA12CA1CA2CA9CA6
SCHEMBL15521795 0.88 MRGPRX4 (0.43) CA12CA1CA2CA7CA9
SCHEMBL5141318 0.87 CA12 (0.44) CA12CA1CA2CA7CA9
SCHEMBL17354771 0.87 RARB (0.46) CA12CA1CA2CA7CA9
SCHEMBL2707734 0.86 APP (0.52) TSHRRARBRARGPTPN11
SCHEMBL4367063 0.86 APP (0.52) MAPTTSHRRARBRARGPTPN11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250188521-A1 NUCLEIC ACID DELIVERY SCAFFOLDS Singular Genomics Systems, Inc. 2025-06-12 US disclosed
US-12188088-B1 Multiplexed targeted amplification of polynucleotides Singular Genomics Systems, Inc. (US) 2025-01-07 US disclosed
US-20240425919-A1 MULTIPLEXED TARGETED AMPLIFICATION OF POLYNUCLEOTIDES FIRST-CITIZENS BANK & TRUST COMPANY 2024-12-26 US disclosed
EP-4422792-A1 MULTIPLEXED TARGETED AMPLIFICATION OF POLYNUCLEOTIDES Singular Genomics Systems, Inc. (US) 2024-09-04 EP disclosed
US-20240240251-A1 MULTIPLEXED TARGETED AMPLIFICATION OF POLYNUCLEOTIDES FIRST-CITIZENS BANK & TRUST COMPANY 2024-07-18 US disclosed
US-20230399692-A1 NUCLEIC ACID DELIVERY SCAFFOLDS FIRST-CITIZENS BANK & TRUST COMPANY 2023-12-14 US disclosed
US-11795505-B2 Nucleic acid delivery scaffolds Singular Genomics Systems, Inc. (US) 2023-10-24 US disclosed
CN-116925369-A Method for preparing nanoscale hydrogen bond organic framework and composite material based on mechanical ball milling method 中国科学院福建物质结构研究所 2023-10-24 CN disclosed
US-20230287491-A1 NUCLEIC ACID DELIVERY SCAFFOLDS FIRST-CITIZENS BANK & TRUST COMPANY 2023-09-14 US disclosed
WO-2023172665-A2 NUCLEIC ACID DELIVERY SCAFFOLDS Singular Genomics Systems, Inc. (US) 2023-09-14 WO disclosed
WO-2023076833-A1 MULTIPLEXED TARGETED AMPLIFICATION OF POLYNUCLEOTIDES Singular Genomics Systems, Inc. (US) 2023-05-04 WO disclosed
US-11077327-B1 Degradation of chemical agents using metal-organic framework compositions NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) 2021-08-03 US disclosed
US-20210231628-A1 PHOTOLUMINESCENCE-BASED DETECTION OF ACID GASES VIA RARE EARTH METAL-ORGANIC FRAMEWORKS NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC 2021-07-29 US disclosed
US-11007516-B1 Tunable metal-organic framework compositions and methods thereof NATIONAL TECHNOLOGY & ENGINEERING SOLUTIONS OF SANDIA, LLC (US) 2021-05-18 US disclosed