Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 6/20 | 0.49 |
| ▸ | PDE2A | O00408 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | PDE4A | P27815 | 1/20 | 0.49 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23561539 | 1.00 | ADA (0.49) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL22106710 | 0.88 | ADA (0.51) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL19661763 | 0.88 | CDK1 (0.58) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL18649621 | 0.88 | CDK1 (0.58) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL21078562 | 0.86 | ADA (0.48) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL22166097 | 0.84 | ADA (0.46) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL19661690 | 0.84 | ADA (0.46) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL21945758 | 0.81 | ADA (0.71) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL24971291 | 0.81 | ADA (0.71) | ADAPDE2ACYP3A4PDE4APDE4B | |
| SCHEMBL22106688 | 0.81 | ADA (0.71) | ADAPDE2ACYP3A4PDE4APDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11338041-B2 | Exon skipping oligomer conjugates for muscular dystrophy | SAREPTA THERAPEUTICS, INC. (US) | 2022-05-24 | — | — | US | disclosed |
| US-20210187003-A1 | EXON SKIPPING OLIGOMERS FOR MUSCULAR DYSTROPHY | SAREPTA THERAPEUTICS, INC. | 2021-06-24 | — | — | US | disclosed |
| US-20210138079-A1 | EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY | SAREPTA THERAPEUTICS, INC. (US) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11338041-B2 | Exon skipping oligomer conjugates for muscular dystrophy | SMN1; SMN2, UTRN, RBM17 | ADA 1642/4885PDE2A 3754/4885CYP3A4 4429/4885 |
| US-20210138079-A1 | EXON SKIPPING OLIGOMER CONJUGATES FOR MUSCULAR DYSTROPHY | SMN1; SMN2, UTRN, RBM17 | ADA 1642/4885PDE2A 3754/4885CYP3A4 4429/4885 |
| US-20210187003-A1 | EXON SKIPPING OLIGOMERS FOR MUSCULAR DYSTROPHY | RBM17, UTRN, UPF1 | ADA 2500/4885PDE2A 3494/4885CYP3A4 4808/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.