SCHEMBL23347641

SCHEMBL23347641

CCC(OC(N)=O)[C@@H](O)c1ccccc1Cl

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CASP1 P29466 1/20 0.45
AOC3 Q16853 1/20 0.41
ADRB2 P07550 2/20 0.38
ADRB1 P08588 2/20 0.38
CYP2D6 P10635 1/20 0.37
NFKB1 P19838 1/20 0.37
HIF1A Q16665 1/20 0.37
NISCH Q9Y2I1 1/20 0.36
BLM P54132 1/20 0.36
CXCL8 P10145 1/20 0.36
ALDH1A1 P00352 1/20 0.35
KCNQ2 O43526 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
KMT2A Q03164 1/20 0.34
ATM Q13315 1/20 0.34
IDO1 P14902 1/20 0.34
TDO2 P48775 1/20 0.34
IDO2 Q6ZQW0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3437243 1.00 CASP1 (0.45) CASP1AOC3ADRB2ADRB1CYP2D6
SCHEMBL3434095 1.00 CASP1 (0.45) CASP1AOC3ADRB2ADRB1CYP2D6
SCHEMBL3437161 1.00 CASP1 (0.45) CASP1AOC3ADRB2ADRB1CYP2D6
SCHEMBL15078242 0.89 CYP1A2 (0.41) CASP1AOC3CYP2D6NFKB1HIF1A
SCHEMBL10119422 0.86 CASP1 (0.41) CASP1AOC3ADRB2ADRB1CYP2D6
SCHEMBL3434882 0.86 CASP1 (0.41) CASP1AOC3ADRB2ADRB1CYP2D6
SCHEMBL18568026 0.86 CASP1 (0.41) CASP1AOC3ADRB2ADRB1CYP2D6
SCHEMBL3434560 0.86 CASP1 (0.41) CASP1AOC3ADRB2ADRB1CYP2D6
SCHEMBL15078572 0.85 CASP1 (0.42) CASP1AOC3ADRB2ADRB1NISCH
SCHEMBL23347543 0.85 ALDH1A1 (0.42) CASP1ALDH1A1L3MBTL1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2968211-B1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING EPILEPSY OR EPILEPSY-RELATED SYNDROME BIO PHARM SOLUTIONS CO LTD (KR) 2021-05-12 EP disclosed