Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 3/20 | 0.60 |
| ▸ | CPB1 | P15086 | 1/20 | 0.58 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.58 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | SIRT1 | Q96EB6 | 4/20 | 0.55 |
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.53 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18806287 | 0.90 | FOLH1 (0.59) | FOLH1CPB1CPB2CA1CA2 | |
| SCHEMBL18806289 | 0.89 | FOLH1 (0.58) | FOLH1CPB1CPB2CA1CA2 | |
| SCHEMBL17244715 | 0.88 | SIRT5 (0.62) | FOLH1SIRT1SIRT2SIRT3HTT | |
| SCHEMBL18806288 | 0.88 | CPB1 (0.58) | FOLH1CPB1CPB2CA1CA2 | |
| SCHEMBL18789040 | 0.88 | FOLH1 (0.57) | FOLH1CPB1CPB2CA1CA2 | |
| SCHEMBL18782954 | 0.87 | FOLH1 (0.56) | FOLH1CPB1CPB2CA1CA2 | |
| SCHEMBL18789049 | 0.87 | CAPN1 (0.63) | SIRT5 | |
| SCHEMBL17694108 | 0.86 | SIRT2 (0.68) | SIRT1SIRT2SIRT3 | |
| SCHEMBL18789038 | 0.85 | FOLH1 (0.59) | FOLH1SIRT1SIRT2SIRT3HTT | |
| SCHEMBL18806286 | 0.85 | FOLH1 (0.61) | FOLH1CPB1CPB2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3129014-B1 | NOVEL ORGANOSELENIUM COMPOUNDS, METHOD FOR PRODUCING SAME, AND PHARMACEUTICAL USES THEREOF AS ANTITUMOUR AGENTS | TETRAHEDRON (FR) | 2021-05-12 | — | — | EP | disclosed |