Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 7/20 | 0.46 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | XBP1 | P17861 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23810503 | 1.00 | ALDH1A1 (0.51) | ALDH1A1MAPTLMNABRD4HPGD | |
| SCHEMBL30012539 | 0.87 | BRD4 (0.49) | ALDH1A1MAPTLMNABRD4HPGD | |
| SCHEMBL31498653 | 0.87 | BRD4 (0.49) | ALDH1A1MAPTLMNABRD4HPGD | |
| SCHEMBL31515466 | 0.86 | BRD4 (0.48) | ALDH1A1MAPTLMNABRD4HPGD | |
| SCHEMBL23801148 | 0.85 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNABRD4HPGD | |
| SCHEMBL23801147 | 0.85 | ALDH1A1 (0.58) | ALDH1A1MAPTLMNABRD4HPGD | |
| SCHEMBL872773 | 0.79 | BRD4 (0.49) | ALDH1A1MAPTLMNABRD4HPGD | |
| SCHEMBL872772 | 0.79 | BRD4 (0.49) | ALDH1A1MAPTLMNABRD4HPGD | |
| SCHEMBL30012531 | 0.78 | ALDH1A1 (0.60) | ALDH1A1MAPTLMNABRD4HPGD | |
| SCHEMBL30013082 | 0.77 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAHPGDPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3819305-A1 | AMIDE COMPOUND HAVING BET PROTEOLYSIS-INDUCING ACTION AND MEDICINAL APPLICATION THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2021-05-12 | — | — | EP | disclosed |