Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17059541 | 0.91 | ALDH1A1 (0.44) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL872752 | 0.88 | CASP3 (0.44) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL23728631 | 0.88 | CASP3 (0.44) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL15281424 | 0.88 | CASP3 (0.44) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL29424172 | 0.88 | CASP3 (0.39) | ALDH1A1MAPTLMNAHPGDHTT | |
| SCHEMBL25695323 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL30410248 | 0.88 | ALDH1A1 (0.42) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL15106636 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL2641806 | 0.86 | ALDH1A1 (0.41) | ALDH1A1MAPTLMNAHPGDPLA2G1B | |
| SCHEMBL12152373 | 0.85 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAHPGDPLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022221786-A2 | COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THAT MODULATE BRD4 | Plexium, Inc. (US) | 2022-10-20 | — | — | WO | disclosed |