SCHEMBL23348665

SCHEMBL23348665

CO[Si](CCCCCCN(C)C)(OC)OC

nearest known ligand 0.52

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.52
TSHR P16473 1/20 0.52
DNM1 Q05193 3/20 0.44
LMNA P02545 1/20 0.39
SIGMAR1 Q99720 2/20 0.33
MAOA P21397 1/20 0.33
MAOB P27338 1/20 0.33
HRH4 Q9H3N8 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20730383 1.00 ALDH1A1 (0.52) ALDH1A1TSHRDNM1LMNASIGMAR1
SCHEMBL379316 0.98 ALDH1A1 (0.48) ALDH1A1TSHRDNM1LMNASIGMAR1
SCHEMBL8090320 0.95 ALDH1A1 (0.46) ALDH1A1TSHRDNM1LMNAKDM4E
SCHEMBL31687734 0.91 ALDH1A1 (0.48) ALDH1A1TSHRDNM1LMNASIGMAR1
SCHEMBL27674 0.90 ALDH1A1 (0.43) ALDH1A1TSHRDNM1LMNAKDM4E
Hydrochloric Acid SCHEMBL1969451 0.88 ALDH1A1 (0.41) ALDH1A1TSHRDNM1LMNA
Iodide SCHEMBL26983162 0.88 ALDH1A1 (0.41) ALDH1A1TSHRDNM1LMNA
Bromide SCHEMBL7778868 0.88 ALDH1A1 (0.41) ALDH1A1TSHRDNM1LMNAHRH4
SCHEMBL16862734 0.83 CHRM2 (0.39) LMNA
Dymanthine SCHEMBL1223435 0.83 DNM1 (0.60) ALDH1A1TSHRDNM1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114650882-A Materials and methods for mixed mode anion exchange reverse phase liquid chromatography 沃特世科技公司 2022-06-21 CN disclosed
US-20210138361-A1 MATERIALS AND METHODS FOR MIXED MODE, ANION EXCHANGE REVERSED PHASE LIQUID CHROMATOGRAPHY WATERS TECHNOLOGIES CORPORATION 2021-05-13 US disclosed