Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | GPR3 | P46089 | 2/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL196151 | 0.98 | CYP1A2 (0.48) | CYP1A2KDM4EGPR3EGFRCYP2A6 | |
| Water SCHEMBL27373628 | 0.95 | CYP1A2 (0.47) | CYP1A2KDM4EGPR3EGFRCYP2A6 | |
| Formaldehyde SCHEMBL28015338 | 0.91 | CYP1A2 (0.44) | CYP1A2KDM4EGPR3EGFRCYP2A6 | |
| Piperazine SCHEMBL27739524 | 0.86 | HTR3A (0.42) | CYP1A2KDM4EGPR3EGFRCYP2A6 | |
| SCHEMBL12033738 | 0.78 | CYP1A2 (0.52) | CYP1A2KDM4EGPR3CYP2A6ALDH1A1 | |
| SCHEMBL30059022 | 0.76 | CYP1A2 (0.45) | CYP1A2KDM4EGPR3PDE10AALDH1A1 | |
| SCHEMBL17532748 | 0.75 | LMNA (0.61) | CYP1A2KDM4EGPR3CYP2A6ALDH1A1 | |
| SCHEMBL21959296 | 0.75 | MEN1 (0.42) | KDM4EGPR3CYP2A6PDE10AALDH1A1 | |
| SCHEMBL8404379 | 0.74 | CYP1A2 (0.42) | CYP1A2KDM4EGPR3CYP2A6ALDH1A1 | |
| SCHEMBL30527184 | 0.73 | CYP1A2 (0.60) | CYP1A2KDM4EGPR3EGFRCYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139482-A1 | SUBSTITUTED 1,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONES | RECURIUM IP HOLDINGS, LLC | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139482-A1 | SUBSTITUTED 1,2-DIHYDRO-3H-PYRAZOLO[3,4-D]PYRIMIDIN-3-ONES | MKI67, BRCA1, CCNI | CYP1A2 361/4885KDM4E 2533/4885GPR3 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.