Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 17/20 | 0.54 |
| ▸ | F2 | P00734 | 11/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.46 |
| ▸ | PLAT | P00750 | 1/20 | 0.46 |
| ▸ | PROC | P04070 | 1/20 | 0.46 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2325707 | 0.87 | F10 (0.69) | F10F2PLGPLATPROC | |
| SCHEMBL8423783 | 0.85 | F10 (0.72) | F10F2PLGPLATPROC | |
| SCHEMBL8425358 | 0.85 | F10 (0.59) | F10F2PLGPLATPROC | |
| SCHEMBL2330221 | 0.83 | F10 (0.73) | F10F2PLGPROC | |
| SCHEMBL2328117 | 0.78 | F10 (0.46) | F10F2PLGPLATPROC | |
| SCHEMBL8425665 | 0.77 | F10 (0.46) | F10F2PLGPLATPROC | |
| SCHEMBL2332844 | 0.77 | F10 (0.69) | F10F2PLGPLATPROC | |
| SCHEMBL2328762 | 0.77 | F10 (0.67) | F10F2PLGPLATPROC | |
| SCHEMBL2328912 | 0.76 | F10 (0.73) | F10F2PLGPLATPROC | |
| SCHEMBL2329198 | 0.76 | F10 (0.66) | F10F2PLGPLATPROC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0853618-B1 | SUBSTITUTED (SULFINIC ACID, SULFONIC ACID, SULFONYLAMINO OR SULFINYLAMINO) N- (AMINOIMINOMETHYL)PHENYLALKYL -AZAHETEROCYCLYLAMIDE COMPOUNDS | AVENTIS PHARMA INC (US) | 2011-08-17 | — | — | EP | disclosed |