Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGFR | P43088 | 3/20 | 0.73 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.73 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.73 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.73 |
| ▸ | PTGIR | P43119 | 3/20 | 0.73 |
| ▸ | TSHR | P16473 | 3/20 | 0.73 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.73 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.73 |
| ▸ | HPGD | P15428 | 2/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.73 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.73 |
| ▸ | ESR1 | P03372 | 1/20 | 0.73 |
| ▸ | PGR | P06401 | 1/20 | 0.73 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.73 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.73 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.52 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL674246 | 1.00 | PTGFR (0.73) | PTGFRPTGER3PTGER4PTGER2PTGIR | |
| SCHEMBL10742477 | 1.00 | PTGFR (0.73) | PTGFRPTGER3PTGER4PTGER2PTGIR | |
| SCHEMBL11079261 | 1.00 | PTGFR (0.73) | PTGFRPTGER3PTGER4PTGER2PTGIR | |
| SCHEMBL3368201 | 1.00 | PTGFR (0.73) | PTGFRPTGER3PTGER4PTGER2PTGIR | |
| SCHEMBL29424279 | 1.00 | PTGFR (0.73) | PTGFRPTGER3PTGER4PTGER2PTGIR | |
| SCHEMBL29420457 | 1.00 | PTGFR (0.73) | PTGFRPTGER3PTGER4PTGER2PTGIR | |
| SCHEMBL11379818 | 0.91 | PTGER4 (0.70) | PTGFRPTGER3PTGER4PTGER2PTGIR | |
| Trimoprostil SCHEMBL11024670 | 0.91 | PTGER3 (0.64) | PTGFRPTGER3PTGER4PTGER2PTGIR | |
| Trimoprostil SCHEMBL564049 | 0.91 | PTGER3 (0.64) | PTGFRPTGER3PTGER4PTGER2PTGIR | |
| Trimoprostil SCHEMBL11226793 | 0.91 | PTGER3 (0.64) | PTGFRPTGER3PTGER4PTGER2PTGIR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139435-A1 | PROSTAGLANDIN ANALOGS AND USES THEREOF | Lifex Biolabs, Inc. | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139435-A1 | PROSTAGLANDIN ANALOGS AND USES THEREOF | PTGDR, NR3C1, PTGIR | PTGFR 19/4885PTGER3 23/4885PTGER4 20/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.