Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.47 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.46 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.43 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 4/20 | 0.43 |
| ▸ | PPARD | Q03181 | 4/20 | 0.43 |
| ▸ | PPARA | Q07869 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14725998 | 0.85 | PLA2G2C (0.44) | TSHRLMNANFKB1PMP22PLA2G2C | |
| SCHEMBL20529565 | 0.83 | FAAH (0.66) | TSHRPLA2G2CPLA2G10GPR84MEN1 | |
| SCHEMBL22034034 | 0.83 | FAAH (0.66) | TSHRPLA2G2CPLA2G10GPR84MEN1 | |
| SCHEMBL14331545 | 0.79 | FAAH (0.63) | TSHRLMNANFKB1PMP22PLA2G2C | |
| SCHEMBL71908 | 0.79 | FAAH (0.63) | TSHRLMNANFKB1PMP22PLA2G2C | |
| SCHEMBL15680096 | 0.79 | FAAH (0.63) | TSHRLMNANFKB1PMP22PLA2G2C | |
| SCHEMBL15850011 | 0.79 | FAAH (0.63) | TSHRLMNANFKB1PMP22PLA2G2C | |
| SCHEMBL12295267 | 0.79 | FAAH (0.63) | TSHRLMNANFKB1PMP22PLA2G2C | |
| SCHEMBL15680128 | 0.79 | FAAH (0.63) | TSHRLMNANFKB1PMP22PLA2G2C | |
| SCHEMBL18573713 | 0.78 | MEN1 (0.70) | TSHRLMNANFKB1PMP22PLA2G2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210137874-A1 | MODIFIED PLATINUM COMPOUNDS AND THERAPEUTIC USES THEREOF | UNIV CALIFORNIA (US) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210137874-A1 | MODIFIED PLATINUM COMPOUNDS AND THERAPEUTIC USES THEREOF | TP53, ANXA5, ANXA3 | TSHR 3399/4885LMNA 4394/4885NFKB1 4263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.