Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.63 |
| ▸ | PLA2G10 | O15496 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARD | Q03181 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15850011 | 1.00 | FAAH (0.63) | FAAHPLA2G10SMN1; SMN2SLC6A5MEN1 | |
| SCHEMBL15680128 | 1.00 | FAAH (0.63) | FAAHPLA2G10SMN1; SMN2SLC6A5MEN1 | |
| SCHEMBL15680096 | 1.00 | FAAH (0.63) | FAAHPLA2G10SMN1; SMN2SLC6A5MEN1 | |
| SCHEMBL14331545 | 1.00 | FAAH (0.63) | FAAHPLA2G10SMN1; SMN2SLC6A5MEN1 | |
| SCHEMBL71908 | 1.00 | FAAH (0.63) | FAAHPLA2G10SMN1; SMN2SLC6A5MEN1 | |
| SCHEMBL15602821 | 0.98 | FAAH (0.60) | FAAHPLA2G10SMN1; SMN2SLC6A5MEN1 | |
| SCHEMBL15602822 | 0.98 | FAAH (0.60) | FAAHPLA2G10SMN1; SMN2SLC6A5MEN1 | |
| SCHEMBL4572557 | 0.94 | FAAH (0.56) | FAAHPLA2G10SMN1; SMN2SLC6A5MEN1 | |
| SCHEMBL30838580 | 0.94 | FAAH (0.69) | FAAHPLA2G10SMN1; SMN2SLC6A5MEN1 | |
| SCHEMBL30838579 | 0.94 | FAAH (0.69) | FAAHPLA2G10SMN1; SMN2SLC6A5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210094999-A1 | Novel Acylated Insulin Analogues and Uses Thereof | NOVO NORDISK AS (DK) | 2021-04-01 | — | — | US | disclosed |
| US-10570184-B2 | GLP-1/glucagon receptor co-agonists for medical use | NOVO NORDISK A/S (DK) | 2020-02-25 | — | — | US | disclosed |
| US-20170101454-A1 | GLP-1/Glucagon Receptor Co-Agonists for Medical Use | NOVO NORDISK A/S (DK) | 2017-04-13 | — | — | US | disclosed |
| US-8815802-B2 | GLP-1 analogues and derivatives | NOVO NORDISK A/S (DK) | 2014-08-26 | — | — | US | disclosed |
| US-8815802-B2 | GLP-1 analogues and derivatives | NOVO NORDISK A/S (DK) | 2014-08-26 | — | — | US | disclosed |
| US-20130053311-A1 | GLP-1 ANALOGUES AND DERIVATIVES | NOVO NORDISK A/S (DK) | 2013-02-28 | — | — | US | disclosed |
| US-20130053311-A1 | GLP-1 ANALOGUES AND DERIVATIVES | NOVO NORDISK A/S (DK) | 2013-02-28 | — | — | US | disclosed |
| WO-2011117415-A1 | NOVEL GLUCAGON ANALOGUES | NOVO NORDISK A/S (DK) | 2011-09-29 | — | — | WO | disclosed |
| WO-2011117416-A1 | NOVEL GLUCAGON ANALOGUES | NOVO NORDISK A/S (DK) | 2011-09-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101454-A1 | GLP-1/Glucagon Receptor Co-Agonists for Medical Use | GLP1R, GCGR, GIPR | FAAH 739/4885PLA2G10 1815/4885SMN1; SMN2 3632/4885 |
| US-10570184-B2 | GLP-1/glucagon receptor co-agonists for medical use | GLP1R, GCGR, GIPR | FAAH 755/4885PLA2G10 1816/4885SMN1; SMN2 3640/4885 |
| US-20130053311-A1 | GLP-1 ANALOGUES AND DERIVATIVES | GLP1R, IAPP, SLC5A1 | FAAH 1807/4885PLA2G10 4084/4885SMN1; SMN2 3452/4885 |
| US-20210094999-A1 | Novel Acylated Insulin Analogues and Uses Thereof | IAPP, GPR119, INSR | FAAH 491/4885PLA2G10 1199/4885SMN1; SMN2 2449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.