Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 14/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 14/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | CHUK | O15111 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23353562 | 0.88 | POLB (0.41) | POLBALDH1A1KDM4EHPGDGAA | |
| SCHEMBL23353557 | 0.85 | POLB (0.39) | POLBGRIN1GRIN2BALDH1A1MEN1 | |
| SCHEMBL21610556 | 0.82 | POLB (0.37) | POLBGRIN1GRIN2BALDH1A1KDM4E | |
| SCHEMBL21609571 | 0.79 | POLB (0.46) | POLBGRIN1GRIN2BALDH1A1MEN1 | |
| SCHEMBL30340579 | 0.78 | POLB (0.41) | POLBGRIN1GRIN2BALDH1A1KDM4E | |
| SCHEMBL23353561 | 0.78 | POLB (0.40) | POLBGRIN1GRIN2B | |
| SCHEMBL23351441 | 0.77 | POLB (0.36) | POLBGRIN1GRIN2B | |
| SCHEMBL21609575 | 0.77 | POLB (0.45) | POLBMEN1KMT2A | |
| SCHEMBL19712002 | 0.77 | POLB (0.43) | POLBMEN1KMT2A | |
| SCHEMBL21550152 | 0.77 | POLB (0.43) | POLBALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210139480-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210139480-A1 | HETEROCYCLE DERIVATIVES AS PESTICIDES | DDT, CBR3, CBR1 | POLB 4632/4885GRIN1 1001/4885GRIN2B 1943/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.