SCHEMBL21550152

SCHEMBL21550152

CCS(=O)(=O)c1c(-c2nc3cc(C(F)(F)F)cnc3n2C)nc2ccc(C(F)(F)F)cn12

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.43
TRPA1 O75762 7/20 0.39
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
RXFP1 Q9HBX9 1/20 0.34
ADORA2A P29274 1/20 0.33
EIF2AK4 Q9P2K8 2/20 0.33
S1PR1 P21453 1/20 0.33
NR1H4 Q96RI1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29658134 0.92 TRPA1 (0.36) POLBTRPA1KDM4EALDH1A1RXFP1
SCHEMBL21550144 0.92 POLB (0.41) POLBTRPA1KDM4EALDH1A1RXFP1
SCHEMBL21805955 0.92 POLB (0.41) POLBTRPA1KDM4EALDH1A1
SCHEMBL29358501 0.92 POLB (0.41) POLBTRPA1KDM4EALDH1A1
SCHEMBL21550142 0.92 POLB (0.41) POLBTRPA1
SCHEMBL19712005 0.88 POLB (0.44) POLBALDH1A1S1PR1
SCHEMBL19711919 0.87 POLB (0.42) POLBTRPA1ALDH1A1S1PR1
SCHEMBL19712043 0.87 POLB (0.42) POLB
SCHEMBL19711923 0.85 POLB (0.42) POLB
SCHEMBL21550082 0.85 POLB (0.42) POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250143304-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2025-05-08 US claimed
EP-4475680-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL Syngenta Crop Protection AG (CH) 2024-12-18 EP claimed
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2024-11-28 US claimed
US-12144349-B2 Pesticidal mixtures comprising a mesoionic compound BASF SE (DE) 2024-11-19 US claimed
CN-118922081-A Insect, acarina and nematode pest control 先正达农作物保护股份公司 2024-11-08 CN claimed
CN-117998986-A Insect, acarina and nematode pest control 先正达农作物保护股份公司 2024-05-07 CN claimed
WO-2023152340-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2023-08-17 WO claimed
WO-2019233826-A1 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES BASF SE (DE) 2019-12-12 WO claimed
US-12564191-B2 Pesticidal compounds BASF SE (DE) 2026-03-03 US disclosed
EP-4341258-B1 NEW SUBSTITUTED PYRIDINES AS FUNGICIDES BASF SE (DE) 2025-12-03 EP disclosed
EP-4604730-A1 PYRIDINE COMPOUNDS FOR COMBATTING DIHYDROOROTATE-DEHYDROGENASE INHIBITOR-RESISTANT PHYTOPATHOGENIC FUNGI BASF SE (DE) 2025-08-27 EP disclosed
EP-4565581-A1 PYRAZOLO PESTICIDAL COMPOUNDS BASF SE (DE) 2025-06-11 EP disclosed
CN-120076714-A Pyridine compounds for combating dihydroorotate dehydrogenase inhibitor-resistant phytopathogenic fungi 巴斯夫欧洲公司 2025-05-30 CN disclosed
US-20250143304-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL SYNGENTA CROP PROTECTION AG (CH) 2025-05-08 US disclosed
EP-3769623-A1 MESOIONIC IMIDAZOLIUM COMPOUNDS AND DERIVATIVES FOR COMBATING ANIMAL PESTS BASF SE (DE) 2021-01-27 EP disclosed
EP-3766879-A1 PESTICIDAL PYRAZOLE DERIVATIVES BASF SE (DE) 2021-01-20 EP disclosed
WO-2020244969-A1 PYRIDINE DERIVATIVES AND THEIR USE AS FUNGICIDES BASF SE (DE) 2020-12-10 WO disclosed
EP-3696177-A1 HETEROCYCLIC COMPOUNDS FOR THE CONTROL OF INVERTEBRATE PESTS BASF SE (DE) 2020-08-19 EP disclosed
WO-2019233826-A1 FUNGICIDAL MIXTURES COMPRISING SUBSTITUTED 3-PHENYL-5-(TRIFLUOROMETHYL)-1,2,4-OXADIAZOLES BASF SE (DE) 2019-12-12 WO disclosed
WO-2019214979-A1 SUBSTITUTED TRIFLUOROMETHYLOXADIAZOLES FOR COMBATING PHYTOPATHOGENIC FUNGI BASF SE (DE) 2019-11-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12564191-B2 Pesticidal compounds CBR1, CBR3, SCN1B POLB 4047/4885TRPA1 673/4885KDM4E 3982/4885
US-20240389596-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL ACACA, ACAT2, ACAT1 POLB 4410/4885TRPA1 1093/4885KDM4E 2817/4885
US-20250143304-A1 INSECT, ACARINA AND NEMATODE PEST CONTROL ACACA, ACAT2, ACAA2 POLB 4472/4885TRPA1 1037/4885KDM4E 3450/4885
US-12144349-B2 Pesticidal mixtures comprising a mesoionic compound ACHE, DDT, MTX2 POLB 2186/4885TRPA1 79/4885KDM4E 4556/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.